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AB SCIEX QTRAP 4500 LC-MS/MS hybrid triple quadrupole linear ion trap system for targeted quantitation and qualitative workflows in pharmaceutical, food safety, environmental, and clinical toxicology research.
  • AB SCIEX QTRAP 4500 LC-MS/MS hybrid triple quadrupole linear ion trap system for targeted quantitation and qualitative workflows in pharmaceutical, food safety, environmental, and clinical toxicology research.
  • AB SCIEX QTRAP 4500 LC-MS/MS hybrid triple quadrupole linear ion trap system for targeted quantitation and qualitative workflows in pharmaceutical, food safety, environmental, and clinical toxicology research.
AB SCIEX QTRAP 4500 LC-MS/MS
$0.00

Key Features:

  • QTRAP Hybrid Design: Combines triple quadrupole quantitation with linear ion trap (LIT) scanning, providing both targeted quantitation and advanced qualitative workflows.

  • Sensitivity Upgrade: Up to 10× higher sensitivity compared to the 3200 series, enabling low-level quantitation in complex samples.

  • High-Speed MRM: Supports up to 1000 MRM transitions/sec, optimized for UHPLC workflows with narrow peaks.

  • Enhanced Product Ion (EPI) Scanning: Enables structural elucidation for metabolites, impurities, and unknowns.

  • MS³ Capability: Linear ion trap allows MS/MS/MS scans for deeper structural information.

  • Polarity Switching: <50 ms, enabling positive/negative detection within one analysis.

  • Turbo V™ Ion Source: Stable, high-efficiency ionization with interchangeable ESI and APCI probes.

  • Compact & Efficient: Mid-range QTRAP system designed for labs requiring both quantitative and qualitative performance.

  • Software Ecosystem: SCIEX Analyst® and MultiQuant™ for data acquisition, quantitation, and compliance-ready reporting.

  • Regulatory Compliance: Fully supports FDA 21 CFR Part 11 and GLP/GMP requirements.

Applications:

  • Pharmaceutical & Biopharma: Drug discovery, DMPK, bioanalysis, impurity profiling, metabolite identification.

  • Food Safety & Agriculture: Quantification of pesticide residues, mycotoxins, veterinary drugs, and contaminants.

  • Environmental Testing: Detection of pharmaceuticals, endocrine disruptors, and pollutants in environmental samples.

  • Clinical & Forensic Toxicology: Targeted drug testing, forensic screening, biomarker quantitation.

  • Metabolomics & Lipidomics: Targeted metabolite and lipid quantitation with confirmatory EPI scans.

  • Academic & Research Labs: Hybrid workflows combining quantitation with structural elucidation.

Specifications (Table):

Parameter Specification
System Configuration AB SCIEX QTRAP 4500 LC-MS/MS
MS Type Hybrid Triple Quadrupole – Linear Ion Trap (QTRAP)
Mass Range m/z 5 – 2000
Resolution Unit resolution (0.7 Da FWHM)
Dynamic Range ~5 orders of magnitude
Ionization Modes Turbo V™ Source (ESI, APCI)
Polarity Switching <50 ms
Acquisition Modes MRM, SIM, EPI, MS³, Precursor Ion Scan, Neutral Loss Scan
MRM Transition Speed Up to 1000 transitions/sec
Sensitivity (LOQ) fg–pg level (compound dependent)
Collision Cell Q2 linear collision cell
Vacuum System Turbo molecular pumping system
Front-End LC Compatible with UHPLC/HPLC systems (e.g., Shimadzu Nexera, Agilent 1260/1290)
Autosampler Compatible with common UHPLC autosamplers
Interface Turbo V ion source with orthogonal spray design
Software SCIEX Analyst®, MultiQuant™
Compliance 21 CFR Part 11, GLP/GMP ready


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