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Key Features:
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Next-Generation Quantitation Power: Builds on the legacy of the SCIEX 6500, delivering sub-femtogram sensitivity for the most demanding applications.
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OptiFlow® Turbo V Source: Supports both microflow and standard flow LC seamlessly, maximizing flexibility and sensitivity.
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SelexION® Differential Mobility Technology (DMS): Optional add-on for increased selectivity by separating isobaric compounds before MS analysis.
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Fast Polarity Switching: <5 ms for efficient acquisition in mixed-ion workflows.
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High-Speed Acquisition: Up to 5,000 MRM transitions/sec with ultra-fast cycle times for multiplexed assays.
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Increased Dynamic Range: Wide linear range enables quantification of analytes from trace levels to high abundance.
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Robust Design: Optimized ion optics and collision cell (LINAC® technology) reduce crosstalk and maximize throughput.
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Data Integrity: Supports 21 CFR Part 11 compliance, making it suitable for regulated labs.
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Analyst® and SCIEX OS Software: Advanced data acquisition, processing, and compliance-ready reporting.
Applications:
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Pharmaceutical & Biopharma R&D: Pharmacokinetics, bioequivalence, metabolite identification, impurity profiling.
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Food Safety Testing: Residues of pesticides, veterinary drugs, and contaminants at ultra-trace levels.
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Environmental Monitoring: Quantitation of pollutants, persistent organic contaminants, and emerging trace chemicals.
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Clinical & Forensic Research: Toxicology, therapeutic drug monitoring, forensic drug screening.
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Biological Studies: Targeted metabolomics, lipidomics, and proteomics with microflow LC compatibility.
Specifications (Table):
| Parameter | Specification |
|---|---|
| MS Type | Triple Quadrupole LC-MS/MS |
| Mass Range | m/z 5 – 2,000 |
| Resolution | Unit resolution (0.7 Da FWHM) |
| Polarity Switching | <5 ms |
| Dynamic Range | >6 orders of magnitude |
| MRM Transitions | Up to 5,000 transitions/sec |
| Acquisition Modes | MRM, Product Ion, Precursor Ion, Neutral Loss, Full Scan |
| Ionization Sources | Turbo V™, OptiFlow® Turbo V, DuoSpray®, APCI |
| SelexION® Technology | Optional – Differential Ion Mobility for improved selectivity |
| Collision Cell | LINAC® collision cell technology |
| Vacuum System | Dual turbomolecular pumps |
| Software | Analyst® and SCIEX OS |
| Compliance | 21 CFR Part 11, GLP/GMP ready |