Key Features:

• Hybrid Quadrupole-TOF Design: Combines high selectivity quadrupole filtering with TOF-based high-resolution accurate mass (HRAM) analysis.

• High-Resolution & Accuracy: >30,000 FWHM resolution with sub-ppm mass accuracy for confident compound identification.

• Ultra-Fast Acquisition: Capable of >100 spectra/sec, supporting ultra-high-throughput LC workflows.

• SWATH® DIA (Data-Independent Acquisition): Comprehensive, reproducible proteomic and metabolomic quantification with superior depth and coverage.

• Extended Dynamic Range: >5 orders of magnitude, enabling simultaneous detection of trace and high-abundance analytes.

• Advanced Sensitivity: Optimized optics and detection system deliver increased ion transmission and sensitivity compared to earlier models (e.g., TripleTOF 5600+).

• Versatile Scan Modes: Full MS, IDA (Information Dependent Acquisition), MS/MSALL, SWATH DIA, and Product Ion scans.

• Dual Ionization Sources: Compatible with Turbo V™ and DuoSpray® for flexible ESI and APCI workflows.

• Fast Polarity Switching: <50 ms for efficient dual-mode experiments.

• Robust Design: Engineered for reproducibility, uptime, and long-term stability in high-throughput environments.

• Software Integration: SCIEX OS and Analyst® TF for acquisition, analysis, and compliance in regulated environments.

Applications:

• Proteomics: Deep protein identification, quantitative proteomics, biomarker discovery, large-cohort SWATH DIA studies.

• Metabolomics & Lipidomics: Untargeted and targeted profiling of metabolites and lipids.

• Pharmaceutical R&D: Drug metabolism, pharmacokinetics (DMPK), impurity identification, and lead compound screening.

• Clinical & Translational Research: Large-scale biomarker studies, disease mechanism exploration, and validation research.

• Food & Environmental Analysis: High-resolution screening of pesticides, toxins, contaminants, and environmental pollutants.

Specifications (Table):