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Agilent 1100 Series HPLC System with quaternary pump, autosampler, column oven, and diode array detector reliable modular HPLC system for pharmaceutical, food, environmental, and industrial chromatography applications.
  • Key Features:

    • Modular and flexible Agilent 1100 Series HPLC system configured with quaternary gradient pump, autosampler, thermostatted column compartment, and diode array detector (DAD).

    • Quaternary pump enables mixing of up to four solvents, supporting isocratic and gradient methods for maximum flexibility in method development.

    • High-pressure mixing and degassing ensure reproducible gradients and stable baselines.

    • Autosampler offers precise and reproducible injections with programmable injection volumes and high sample capacity for unattended operation.

    • Column oven (thermostatted compartment) provides precise column temperature control for improved reproducibility and method robustness.

    • DAD detector offers spectral acquisition across a wide wavelength range (typically 190–950 nm) with high sensitivity, resolution, and spectral deconvolution for peak purity analysis.

    • Designed for ruggedness and reliability in routine and advanced chromatographic workflows.

    • Compatible with a wide range of columns and chemistries, supporting reversed-phase, normal-phase, ion-exchange, size-exclusion, and specialty modes.

    • Fully integrated with Agilent ChemStation software for control, data acquisition, and reporting, with compliance support for regulated laboratories (21 CFR Part 11).

  • Applications:

    • Pharmaceutical & Biotech: Drug development, stability testing, impurity profiling, dissolution testing, bioanalysis of small molecules.

    • Food & Beverage Analysis: Determination of vitamins, preservatives, sweeteners, additives, pesticides, and contaminants.

    • Environmental Testing: Analysis of pesticides, herbicides, endocrine disruptors, and pollutants in water, soil, and air.

    • Chemical & Industrial: QA/QC of raw materials, intermediates, and specialty chemicals.

    • Clinical & Biomedical Research: Analysis of metabolites, amino acids, peptides, nucleotides, and biomarkers.

    • Academic Research: General chromatography for teaching, R&D, and advanced analytical method development.

  • Specifications:

Parameter Specification
System Type High-Performance Liquid Chromatography (HPLC)
Pump Quaternary gradient pump (mixing up to 4 solvents)
Flow Range Typically 0.001–10 mL/min (depending on module version)
Pressure Range Up to 400 bar (standard quaternary pump)
Degasser Built-in vacuum degassing unit
Autosampler Injection volume range: 0.1–100 µL (programmable), high sample capacity
Column Oven Thermostatted compartment, 10–80°C (extendable with options)
Detector Diode Array Detector (DAD), spectral range: 190–950 nm, bandwidth ≤ 1 nm
Wavelength Accuracy ± 1 nm
Software Agilent ChemStation, OpenLab CDS
Compliance GLP/GMP, 21 CFR Part 11

 

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