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Agilent 6224 TOF LC/MS with 1260 Infinity II LC versatile accurate-mass time-of-flight mass spectrometry system for pharmaceutical, proteomics, metabolomics, food safety, and environmental applications.
  • Agilent 6224 TOF LC/MS with 1260 Infinity II LC versatile accurate-mass time-of-flight mass spectrometry system for pharmaceutical, proteomics, metabolomics, food safety, and environmental applications.
  • Agilent 6224 TOF LC/MS with 1260 Infinity II LC versatile accurate-mass time-of-flight mass spectrometry system for pharmaceutical, proteomics, metabolomics, food safety, and environmental applications.
Agilent 6224 TOF LC/MS with 1260 Infinity II LC Versatile Accurate Mass Analysis
$0.00

Key Features:

  • Accurate Mass Detection: High-resolution TOF analyzer enabling precise measurement of molecular ions and fragment ions.

  • Versatile Applications: Designed for both qualitative and quantitative accurate-mass LC/MS workflows.

  • Coupled with Agilent 1260 Infinity II LC: Delivers reliable chromatographic separation with advanced pumping systems, low dispersion flow paths, and precise sample injections.

  • Wide Dynamic Range: Supports detection of analytes across diverse concentration ranges in complex samples.

  • Fast Data Acquisition: Optimized for rapid chromatographic runs with accurate mass confirmation.

  • Robust Ion Optics: Efficient ion transfer for improved sensitivity and mass accuracy.

  • Electrospray and APCI Sources: Flexibility for a wide range of compound classes.

  • Mass Accuracy: Sub-ppm level with internal calibration for reliable compound identification.

  • Software Integration: Compatible with Agilent MassHunter suite for acquisition, data processing, and compliance.

  • Regulatory Compliance: Supports 21 CFR Part 11 for regulated laboratory environments.

Applications:

  • Pharmaceutical & Biopharma: Accurate mass confirmation of drug candidates, impurity identification, drug metabolism studies.

  • Proteomics & Metabolomics: Peptide and metabolite identification, biomarker discovery.

  • Environmental Testing: Identification of emerging contaminants, pollutants, and unknowns.

  • Food Safety: Screening for contaminants, pesticides, and adulterants.

  • Forensic & Clinical Research: Small molecule toxicology screening, biomarker analysis.

Specifications (Table):

Parameter Specification
System Configuration Agilent 6224 TOF LC/MS + Agilent 1260 Infinity II LC
MS Type Time-of-Flight (TOF) Mass Spectrometer
Mass Range m/z ~20 – 20,000 (depending on configuration)
Resolution High resolution TOF
Mass Accuracy Sub-ppm with internal reference mass
Dynamic Range 4–5 orders of magnitude
Ionization Modes ESI, APCI
Acquisition Modes Full scan TOF MS, MS/MS (with optional Q-TOF upgrade)
Data Acquisition Speed Optimized for fast UHPLC gradients
Front-End LC Agilent 1260 Infinity II LC (binary pump, autosampler, thermostatted column compartment, DAD/UV detector)
Autosampler Precision ≤0.25% RSD
Flow Range 0.001 – 5 mL/min
Gradient Precision ≤0.05% RSD
Interface ESI/APCI ion sources
Software Agilent MassHunter Workstation
Compliance 21 CFR Part 11, GLP/GMP support


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