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Agilent 6230B TOF LC/MS with 1290 Infinity II UHPLC advanced high-resolution accurate mass time-of-flight LC-MS system for pharmaceutical research, proteomics, metabolomics, food safety, and environmental analysis
  • Key Features:

    • The Agilent 6230B TOF LC/MS delivers high-resolution, accurate-mass measurements for both qualitative and quantitative workflows.

    • Integrated with the Agilent 1290 Infinity II UHPLC, it provides ultra-fast, high-resolution separations to support high-throughput and complex analyses.

    • Offers resolving power >20,000 FWHM with sub-ppm mass accuracy for confident identification.

    • Wide dynamic range for simultaneous quantitation of high- and low-abundance analytes.

    • Equipped with dual ionization options (ESI, APCI) for maximum flexibility.

    • Supports advanced acquisition modes including full scan, MS-only, and exact mass filtering.

    • Enhanced data processing with Agilent MassHunter software, enabling comprehensive qualitative and quantitative analysis.

    • Designed for omics research, environmental analysis, and pharmaceutical development requiring accurate mass confirmation.

    • Fully compliant with GLP/GMP and 21 CFR Part 11 regulations.

  • Applications:

    • Proteomics & Metabolomics: Discovery workflows, biomarker identification, pathway analysis.

    • Pharmaceutical R&D: Drug metabolism, impurity profiling, and accurate mass confirmation.

    • Food Safety Testing: Identification of contaminants, adulterants, and residues.

    • Environmental Monitoring: Detection of trace pollutants and unknown compounds.

    • Chemical and Material Sciences: Exact mass confirmation for complex mixtures.

  • Specifications:

Specification Detail
LC/MS Platform Agilent 6230B TOF LC/MS with 1290 Infinity II UHPLC
MS System Type Time-of-Flight (TOF) Mass Spectrometer
Resolving Power >20,000 FWHM
Mass Range m/z 20–20,000 (extended range available)
Mass Accuracy ≤ 2 ppm (with internal mass calibration)
Ionization Modes ESI, APCI interchangeable
LC System Agilent 1290 Infinity II UHPLC – ultra-high performance separations
Autosampler Agilent 1290 Infinity II autosampler
Acquisition Modes Full scan, exact mass filtering, MS-only
Dynamic Range >5 orders of magnitude
Scan Speed Up to 30 spectra/sec for high-throughput analyses
Vacuum System High-efficiency turbomolecular pump
Interface Orthogonal spray ionization with optimized ion optics
Software Agilent MassHunter Qualitative & Quantitative Suite
Compliance 21 CFR Part 11 compatible

 

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