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Bruker Impact II Q-TOF LC-MS/MS with Elute UHPLC high-resolution quadrupole time-of-flight LC-MS system for proteomics, metabolomics, pharmaceutical, and biopharma applications.
  • Bruker Impact II Q-TOF LC-MS/MS with Elute UHPLC high-resolution quadrupole time-of-flight LC-MS system for proteomics, metabolomics, pharmaceutical, and biopharma applications.
  • Bruker Impact II Q-TOF LC-MS/MS with Elute UHPLC high-resolution quadrupole time-of-flight LC-MS system for proteomics, metabolomics, pharmaceutical, and biopharma applications.
Bruker Impact II Q-TOF LC-MS/MS with Elute UHPLC High-Resolution LC-MS System
$0.00

Key Features:

  • Integrated UHPLC-QTOF System: Seamlessly combines the Bruker Impact II Q-TOF with Bruker Elute UHPLC for an optimized, high-resolution LC-MS/MS workflow.

  • High Resolution & Accuracy: Resolution up to 50,000 FWHM with <1 ppm mass accuracy for confident compound identification.

  • Ultra-Fast Acquisition: Spectral acquisition speeds up to 50 Hz, supporting rapid UHPLC separations.

  • True Isotopic Fidelity (TIF): Accurate isotopic pattern matching for robust formula confirmation.

  • High Dynamic Range: More than 5 orders of magnitude dynamic range, suitable for both trace analytes and abundant species.

  • Elute UHPLC Performance: Supports pressures up to 1300 bar, with flexible column choices for sharp peak resolution and robust chromatographic performance.

  • Versatile Ion Sources: ESI, nanoESI, APCI, and APPI ionization options for broad application coverage.

  • Advanced Data Processing: Integrated with Compass DataAnalysis, MetaboScape, ProteinScape, and BioPharma Compass for comprehensive analysis.

  • Regulatory Compliance: 21 CFR Part 11 ready for use in regulated labs.

  • Robustness & Reliability: Built for high-throughput environments with consistent performance and reduced downtime.

Applications:

  • Proteomics & Biopharma: Peptide/protein identification, post-translational modification (PTM) mapping, monoclonal antibody (mAb) analysis.

  • Metabolomics & Lipidomics: Untargeted metabolite profiling, biomarker discovery, lipid pathway analysis.

  • Pharmaceutical Analysis: Drug discovery, metabolite identification, pharmacokinetics (PK), impurity profiling.

  • Food Safety & Environmental: Detection of pesticides, contaminants, toxins, and residues with high sensitivity.

  • Clinical & Translational Research: Biomarker validation, personalized medicine, disease mechanism studies.

Specifications (Table):

Parameter Specification
MS Type Quadrupole Time-of-Flight (QTOF)
Mass Range m/z 50 – 20,000
Resolution Up to 50,000 FWHM
Mass Accuracy <1 ppm (internal calibration)
Acquisition Speed Up to 50 Hz
Dynamic Range >5 orders of magnitude
UHPLC System Bruker Elute UHPLC (1300 bar, sub-2 µm columns)
Ionization Sources ESI, nanoESI, APCI, APPI
Fragmentation Modes CID (Collision-Induced Dissociation)
Software Compass DataAnalysis, MetaboScape, ProteinScape, BioPharma Compass
Compliance 21 CFR Part 11 ready
Detector Technology True Isotopic Fidelity (TIF) with SmartBeam-II detection

 

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