Skip to product information
Bruker Impact II Q-TOF Mass Spectrometer  high-resolution quadrupole time-of-flight system for proteomics, metabolomics, pharmaceutical, and biopharma applications.

Key Features:

  • High Resolution Performance: Resolution up to 50,000 FWHM with sub-ppm mass accuracy for confident molecular identification.

  • Fast Acquisition Rate: Up to 50 Hz spectra acquisition speed, compatible with ultra-fast UHPLC separations.

  • High Dynamic Range: Linear dynamic range of more than 5 orders of magnitude for quantitation of low- and high-abundance analytes.

  • True Isotopic Fidelity (TIF): Accurate isotopic distribution matching for unambiguous molecular formula determination.

  • SmartBeam-II Technology: Advanced detection system enabling enhanced sensitivity and precise peak shapes.

  • Flexible Ionization Options: Compatible with multiple ion sources including ESI, nanoESI, APCI, and APPI.

  • Software Integration: Powered by Bruker Compass DataAnalysis, MetaboScape, ProteinScape, and BioPharma Compass for end-to-end data processing.

  • Regulatory Ready: Supports 21 CFR Part 11 compliance for regulated laboratory environments.

  • Robust Design: Optimized for long-term stability, reliability, and reduced maintenance in high-throughput labs.


Applications:

  • Proteomics & Biopharma: Protein/peptide identification, glycosylation and PTM analysis, intact protein characterization.

  • Metabolomics & Lipidomics: Untargeted profiling, biomarker discovery, pathway elucidation.

  • Pharmaceutical Analysis: Impurity profiling, drug metabolism and pharmacokinetics (DMPK), metabolite identification.

  • Food & Environmental Testing: Contaminant analysis, pesticide residue detection, mycotoxin testing.

  • Clinical Research: Biomarker discovery, translational medicine, disease pathway investigation.


Specifications (Table):

Parameter Specification
MS Type Quadrupole Time-of-Flight (QTOF)
Mass Range m/z 50 – 20,000
Resolution Up to 50,000 FWHM
Mass Accuracy <1 ppm (internal calibration)
Acquisition Speed Up to 50 Hz
Dynamic Range >5 orders of magnitude
Ionization Sources ESI, nanoESI, APCI, APPI
Fragmentation Modes CID (Collision-Induced Dissociation)
Software Bruker Compass DataAnalysis, MetaboScape, ProteinScape, BioPharma Compass
Compliance 21 CFR Part 11 ready
Detector Technology Advanced detection with True Isotopic Fidelity (TIF)

 

You may also like