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Bruker Impact II Q-TOF with Agilent 1290 Infinity II UHPLC high-resolution LC-MS/MS system for proteomics, metabolomics, pharmaceutical, and biopharma applications.
  • Bruker Impact II Q-TOF with Agilent 1290 Infinity II UHPLC high-resolution LC-MS/MS system for proteomics, metabolomics, pharmaceutical, and biopharma applications.
  • Bruker Impact II Q-TOF with Agilent 1290 Infinity II UHPLC high-resolution LC-MS/MS system for proteomics, metabolomics, pharmaceutical, and biopharma applications.
Bruker Impact II Q-TOF with Agilent 1290 Infinity II UHPLC LC-MS System
$0.00

Key Features:

  • Integrated High-Performance System: Combines the Bruker Impact II Q-TOF with Agilent 1290 Infinity II UHPLC for robust LC-MS/MS workflows.

  • High Resolution: Provides up to 50,000 FWHM resolution with <1 ppm mass accuracy for confident identification and quantitation.

  • Fast Acquisition: Achieves up to 50 Hz spectral acquisition, enabling compatibility with ultra-fast UHPLC gradients.

  • Superior Chromatography: Agilent 1290 Infinity II UHPLC delivers up to 1300 bar pressure with sub-2 µm particle columns for sharp separations.

  • True Isotopic Fidelity (TIF): Ensures accurate isotopic pattern recognition and reliable molecular formula confirmation.

  • High Dynamic Range: More than 5 orders of magnitude, supporting trace-level and high-abundance compound analysis.

  • Ionization Flexibility: ESI, nanoESI, APCI, and APPI for broad application coverage.

  • Data Processing Ecosystem: Compatible with Bruker Compass DataAnalysis, MetaboScape, ProteinScape, and BioPharma Compass software.

  • Regulatory Support: 21 CFR Part 11 ready, suitable for GxP and regulated pharmaceutical labs.

  • Robust Design: Reliable for long-term use in proteomics, metabolomics, pharma, and environmental applications.

Applications:

  • Proteomics & Biopharma: Peptide/protein identification, glycosylation studies, monoclonal antibody characterization, PTM analysis.

  • Metabolomics & Lipidomics: Comprehensive metabolite and lipid profiling, biomarker discovery, and pathway analysis.

  • Pharmaceutical Development: Drug discovery, metabolite identification, DMPK studies, impurity profiling.

  • Food & Environmental Testing: Monitoring of contaminants, pesticides, residues, and pollutants.

  • Clinical & Translational Research: Biomarker validation, disease mechanism exploration, personalized medicine studies.

Specifications (Table):

Parameter Specification
MS Type Quadrupole Time-of-Flight (QTOF)
Mass Range m/z 50 – 20,000
Resolution Up to 50,000 FWHM
Mass Accuracy <1 ppm (internal calibration)
Acquisition Speed Up to 50 Hz
Dynamic Range >5 orders of magnitude
UHPLC System Agilent 1290 Infinity II (1300 bar, sub-2 µm columns)
Ionization Sources ESI, nanoESI, APCI, APPI
Fragmentation Modes CID (Collision-Induced Dissociation)
Software Compass DataAnalysis, MetaboScape, ProteinScape, BioPharma Compass
Compliance 21 CFR Part 11 ready
Detector Technology True Isotopic Fidelity (TIF), SmartBeam-II detection

 

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