Skip to product information
Bruker maXis Q-TOF LC-MS/MS with Elute UHPLC complete high-resolution LC-MS system for proteomics, metabolomics, pharmaceutical, and biopharma research.

Key Features:

  • Integrated LC-MS Solution: Combines Bruker maXis Q-TOF with Elute UHPLC, designed as a complete, optimized LC-MS/MS workflow.

  • High-Resolution MS: Achieves >60,000 FWHM with sub-ppm mass accuracy for precise molecular identification.

  • Wide Dynamic Range: Greater than 5 orders of magnitude, suitable for both trace-level and high-abundance compounds.

  • Fast UHPLC Separation: Elute UHPLC supports pressures up to 1300 bar and sub-2 µm particle columns for sharp peak resolution.

  • High-Speed Acquisition: Up to 20 Hz scan rate for compatibility with fast UHPLC gradients.

  • Flexible Ionization Options: ESI, nanoESI, APCI, APPI, and MALDI sources.

  • Advanced Fragmentation: Collision-induced dissociation (CID) with optional ETD for comprehensive molecular characterization.

  • Regulatory Ready: Supports 21 CFR Part 11 compliance for pharmaceutical and GxP workflows.

  • Software Ecosystem: Integrated with Bruker Compass DataAnalysis, MetaboScape, ProteinScape, and BioPharma Compass for end-to-end data interpretation.


Applications:

  • Proteomics & Biopharma: Protein and peptide characterization, mAb analysis, glycosylation profiling, and PTM mapping.

  • Metabolomics & Lipidomics: Untargeted and targeted profiling with high resolution and accuracy.

  • Pharmaceutical R&D: Impurity profiling, drug metabolism, pharmacokinetics (DMPK), and small molecule quantitation.

  • Food & Environmental Testing: Detection of contaminants, toxins, and pesticide residues.

  • Clinical & Biomarker Discovery: Sensitive analysis for translational and personalized medicine research.


Specifications (Table):

Parameter Specification
MS Type Quadrupole Time-of-Flight (QTOF) LC-MS/MS
Mass Range m/z 50 – 20,000
Resolution >60,000 FWHM
Mass Accuracy <1 ppm (internal calibration)
Scan Speed Up to 20 Hz
UHPLC System Bruker Elute UHPLC (up to 1300 bar, sub-2 µm particle compatibility)
Ionization Sources ESI, nanoESI, APCI, APPI, MALDI
Fragmentation Modes CID, optional ETD
Dynamic Range >5 orders of magnitude
Software Compass DataAnalysis, MetaboScape, ProteinScape, BioPharma Compass
Compliance 21 CFR Part 11 ready

 

You may also like