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Bruker maXis Q-TOF Mass Spectrometer  high-resolution, accurate mass QTOF LC-MS system for proteomics, metabolomics, pharmaceuticals, and complex biomolecular analysis.

Key Features:

  • High-Resolution QTOF: Provides mass resolution >60,000 FWHM for confident molecular identification.

  • Accurate Mass Measurement: Sub-ppm mass accuracy with internal calibration for reliable formula determination.

  • Fast Acquisition Speed: Suitable for UHPLC applications with scan rates up to 20 Hz, ideal for fast chromatographic separations.

  • Broad Dynamic Range: Linear dynamic range over 5 orders of magnitude for quantifying trace and abundant compounds simultaneously.

  • Dual Ion Funnel Technology: Enhances sensitivity and transmission efficiency.

  • Versatile Ionization Sources: Compatible with ESI, nanoESI, APCI, APPI, and MALDI.

  • MS/MS Fragmentation: Provides high-quality spectra with CID and optional ETD for structural elucidation.

  • Software Integration: Works with Bruker Compass DataAnalysis, MetaboScape, ProteinScape, and BioPharma Compass.

  • Flexibility for Omics: Optimized for proteomics, metabolomics, lipidomics, and glycomics workflows.

  • Regulatory Support: 21 CFR Part 11 compliance-ready for GxP environments.


Applications:

  • Proteomics: High-resolution peptide and protein identification, top-down/bottom-up workflows.

  • Metabolomics & Lipidomics: Comprehensive untargeted and targeted metabolite profiling.

  • Pharmaceutical Research: Drug discovery, impurity profiling, and biopharmaceutical characterization.

  • Glycomics & Biotherapeutics: Characterization of glycans, monoclonal antibodies, and complex biologics.

  • Clinical & Translational Research: Biomarker discovery and validation.

  • Environmental & Food Analysis: Detection of contaminants, pesticides, and trace pollutants.


Specifications (Table):

Parameter Specification
MS Type Quadrupole Time-of-Flight (QTOF) LC-MS
Mass Range m/z 50 – 20,000
Resolution >60,000 FWHM
Mass Accuracy <1 ppm with internal calibration
Scan Speed Up to 20 Hz
Ionization Sources ESI, nanoESI, APCI, APPI, MALDI
Fragmentation Modes CID, optional ETD
Acquisition Modes Full Scan, MS/MS, Data-Dependent Acquisition (DDA), Data-Independent Acquisition (DIA)
Dynamic Range >5 orders of magnitude
Ion Optics Dual Ion Funnel technology
Software Compass DataAnalysis, ProteinScape, MetaboScape, BioPharma Compass
Compliance 21 CFR Part 11 ready


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