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Key Features:
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Hybrid Q-TOF Design: Combines a quadrupole mass filter with TOF detection for high-sensitivity MS/MS experiments.
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High Mass Accuracy: Delivers sub-ppm mass accuracy with internal calibration for reliable molecular formula assignment.
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True Isotopic Fidelity (TIF): Preserves natural isotopic distribution for confident compound confirmation.
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High Dynamic Range: Enables detection of both low-abundance and high-intensity analytes in complex mixtures.
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Fast Acquisition Speed: Compatible with high-throughput LC separations and real-time MS/MS analysis.
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Wide Mass Range: Suitable for analysis of small molecules, peptides, metabolites, and biomolecules.
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Flexible Ionization: Electrospray ionization (ESI) and optional atmospheric pressure ionization (API) sources available.
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Comprehensive Software Integration: Works with Bruker Compass, DataAnalysis, and ProteinScape for qualitative and quantitative workflows.
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Regulatory Compliance: 21 CFR Part 11 ready for pharmaceutical environments.
Applications:
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Pharmaceutical & Drug Discovery: Structural elucidation, impurity profiling, metabolite identification.
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Proteomics: Peptide sequencing, biomarker discovery, post-translational modification (PTM) studies.
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Metabolomics: High-confidence profiling of complex biological mixtures.
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Environmental & Food Safety: Screening for contaminants, toxins, and residues.
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Academic & Research Labs: Advanced Q-TOF system for high-resolution teaching and routine research.
Specifications (Table):
| Parameter | Specification |
|---|---|
| MS Type | Quadrupole Time-of-Flight (Q-TOF) |
| Mass Range | m/z 50 – 20,000 |
| Resolution | >17,500 FWHM |
| Mass Accuracy | <3 ppm (external), <1 ppm (internal) |
| Ionization Source | Electrospray Ionization (ESI), optional API |
| Acquisition Speed | Up to 20 spectra/second |
| Dynamic Range | >4–5 orders of magnitude |
| Software | Compass, DataAnalysis, ProteinScape |
| Compliance | 21 CFR Part 11 ready |
| Special Feature | True Isotopic Fidelity (TIF) |