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Bruker solariX XR FT-ICR Mass Spectrometer

Key Features:

  • eXtreme Resolution (XR) Technology: Delivers resolving power up to 20 million at m/z 400, enabling separation of isotopologues and isobaric species.

  • Advanced ParaCell® ICR Cell: Enhances ion detection sensitivity and resolution for complex mixture analysis.

  • High Magnetic Field Options: Available with 7T, 9.4T, 12T, or 15T superconducting magnets for tailored performance needs.

  • Ultrahigh Mass Accuracy: Achieves sub-ppm accuracy with internal calibration for confident molecular assignments.

  • Versatile Ionization Sources: Supports ESI, MALDI, APCI, APPI, and nanoESI.

  • Comprehensive MS/MS Workflows: Enables ECD, ETD, CID, IRMPD for advanced structural elucidation.

  • Top-Down Proteomics Ready: Capable of intact protein and proteoform analysis, including PTMs.

  • Petroleomics & Complex Mixtures: Industry-leading capability for crude oil and environmental sample characterization.

  • Broad Mass Range: Covers up to m/z 20,000, ideal for large biomolecules and polymers.

  • Data Analysis Software Suite: Compatible with Bruker Compass DataAnalysis, BioPharma Compass, MetaboScape, and SCiLS Lab.

  • Regulatory Compliance: Supports 21 CFR Part 11 for use in regulated labs.


Applications:

  • Proteomics: Top-down proteomics, proteoform mapping, PTM characterization.

  • Metabolomics & Lipidomics: Deep profiling of biological metabolites and lipids.

  • Petroleomics: Ultrafine characterization of hydrocarbons, asphaltenes, and petroleum fractions.

  • Environmental Research: Identifying thousands of organic pollutants in environmental samples.

  • Pharmaceutical Development: Structural elucidation of APIs, impurities, and biopharmaceuticals.

  • Polymers & Materials: Analysis of synthetic and natural macromolecules.

  • Complex Mixture Analysis: Separation and identification of thousands of compounds in one run.


Specifications (Table):

Parameter Specification
MS Type Fourier Transform Ion Cyclotron Resonance (FT-ICR)
Magnet Strength 7T, 9.4T, 12T, or 15T superconducting magnets
Resolving Power Up to 20,000,000 at m/z 400 (XR mode)
Mass Accuracy <1 ppm with internal calibration
Mass Range Up to m/z 20,000
Ionization Sources ESI, nanoESI, APCI, APPI, MALDI
Fragmentation Modes ECD, ETD, CID, IRMPD
Acquisition Modes Full Scan, MS/MS, high-resolution isotopic analysis
Dynamic Range >5 orders of magnitude
ICR Cell Bruker ParaCell®
Vacuum System Multi-stage ultra-high vacuum with turbomolecular pumps
Software Compass DataAnalysis, BioPharma Compass, MetaboScape, SCiLS Lab
Compliance 21 CFR Part 11 ready


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