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Key Features:
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eXtreme Resolution (XR) Technology: Delivers resolving power up to 20 million at m/z 400, enabling separation of isotopologues and isobaric species.
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Advanced ParaCell® ICR Cell: Enhances ion detection sensitivity and resolution for complex mixture analysis.
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High Magnetic Field Options: Available with 7T, 9.4T, 12T, or 15T superconducting magnets for tailored performance needs.
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Ultrahigh Mass Accuracy: Achieves sub-ppm accuracy with internal calibration for confident molecular assignments.
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Versatile Ionization Sources: Supports ESI, MALDI, APCI, APPI, and nanoESI.
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Comprehensive MS/MS Workflows: Enables ECD, ETD, CID, IRMPD for advanced structural elucidation.
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Top-Down Proteomics Ready: Capable of intact protein and proteoform analysis, including PTMs.
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Petroleomics & Complex Mixtures: Industry-leading capability for crude oil and environmental sample characterization.
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Broad Mass Range: Covers up to m/z 20,000, ideal for large biomolecules and polymers.
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Data Analysis Software Suite: Compatible with Bruker Compass DataAnalysis, BioPharma Compass, MetaboScape, and SCiLS Lab.
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Regulatory Compliance: Supports 21 CFR Part 11 for use in regulated labs.
Applications:
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Proteomics: Top-down proteomics, proteoform mapping, PTM characterization.
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Metabolomics & Lipidomics: Deep profiling of biological metabolites and lipids.
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Petroleomics: Ultrafine characterization of hydrocarbons, asphaltenes, and petroleum fractions.
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Environmental Research: Identifying thousands of organic pollutants in environmental samples.
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Pharmaceutical Development: Structural elucidation of APIs, impurities, and biopharmaceuticals.
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Polymers & Materials: Analysis of synthetic and natural macromolecules.
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Complex Mixture Analysis: Separation and identification of thousands of compounds in one run.
Specifications (Table):
| Parameter | Specification |
|---|---|
| MS Type | Fourier Transform Ion Cyclotron Resonance (FT-ICR) |
| Magnet Strength | 7T, 9.4T, 12T, or 15T superconducting magnets |
| Resolving Power | Up to 20,000,000 at m/z 400 (XR mode) |
| Mass Accuracy | <1 ppm with internal calibration |
| Mass Range | Up to m/z 20,000 |
| Ionization Sources | ESI, nanoESI, APCI, APPI, MALDI |
| Fragmentation Modes | ECD, ETD, CID, IRMPD |
| Acquisition Modes | Full Scan, MS/MS, high-resolution isotopic analysis |
| Dynamic Range | >5 orders of magnitude |
| ICR Cell | Bruker ParaCell® |
| Vacuum System | Multi-stage ultra-high vacuum with turbomolecular pumps |
| Software | Compass DataAnalysis, BioPharma Compass, MetaboScape, SCiLS Lab |
| Compliance | 21 CFR Part 11 ready |