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Key Features:
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Ultra-Sensitive Quantitation: SCIEX 5500 Triple Quad delivers industry-proven sensitivity for trace-level analyte detection.
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Integrated SCIEX Workflow: Seamless pairing of the ExionLC AD UHPLC with the 5500 system ensures stable and reproducible LC-MS/MS performance.
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High-Speed UHPLC Separation: ExionLC AD supports up to 1,300 bar pressure for ultra-high-resolution separations and sharp peak shapes.
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Fast Polarity Switching: <20 ms for simultaneous monitoring of positive and negative ions.
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Dynamic MRM (dMRM): Optimizes dwell and cycle times for multi-analyte targeted methods.
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Enhanced Collision Cell: LINAC® technology provides reduced crosstalk and faster ion transmission.
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Robust Turbo V™ Source: Flexible for a wide range of flow rates and compatible with DuoSpray® and APCI.
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Wide Linear Dynamic Range: Quantifies across 5–6 orders of magnitude with excellent accuracy.
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Regulatory Compliance: 21 CFR Part 11 support for data integrity and GLP/GMP-ready workflows.
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High-Throughput Operation: Designed for continuous performance in demanding pharmaceutical, food, and environmental labs.
Applications:
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Pharmaceutical R&D & QA/QC: Pharmacokinetics, drug metabolism, impurity profiling, and bioanalysis.
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Food Safety & Beverage Testing: Pesticides, veterinary drugs, mycotoxins, and contaminants.
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Environmental Monitoring: Quantification of pollutants, trace organic compounds, and emerging contaminants.
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Clinical & Forensic Research: Therapeutic drug monitoring, toxicology screening, and forensic investigations.
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Omics Studies: Targeted metabolomics, lipidomics, and proteomics with high chromatographic resolution.
Specifications (Table):
| Parameter | Specification |
|---|---|
| MS Type | Triple Quadrupole LC-MS/MS |
| Mass Range | m/z 5 – 2,000 |
| Mass Resolution | Unit resolution (0.7 Da FWHM) |
| Polarity Switching | <20 ms |
| Dynamic Range | 5–6 orders of magnitude |
| Scan Speed | Up to 5,000 Da/sec |
| Acquisition Modes | MRM, Product Ion, Precursor Ion, Neutral Loss, Full Scan |
| Ionization Sources | Turbo V™, DuoSpray®, APCI |
| Collision Cell | LINAC® collision cell technology |
| Vacuum System | Dual turbomolecular pumps |
| UHPLC System | ExionLC AD UHPLC |
| UHPLC Pressure | Up to 1,300 bar |
| Flow Rate Range | 0.001 – 5.0 mL/min |
| Column Temperature | 10 – 100 °C |
| Autosampler | ExionLC AD with high-capacity trays and low carryover design |
| Software | SCIEX Analyst® Software with full LC-MS/MS integration |
| Compliance | 21 CFR Part 11, GLP/GMP ready |