Key Features:

• Ultra-Sensitive Quantitation: SCIEX 6500+ achieves sub-femtogram detection limits, making it one of the most sensitive triple quadrupole systems available.

• Shimadzu Nexera UHPLC Front-End: Delivers ultra-fast gradients, high reproducibility, and peak resolution, with pressure tolerance up to 1,300 bar.

• OptiFlow® and Turbo V™ Source: Supports both standard-flow and microflow LC workflows, ensuring maximum flexibility.

• SelexION® Technology (optional): Adds differential ion mobility to reduce matrix interferences and enhance selectivity.

• Rapid Polarity Switching: <5 ms switching allows simultaneous monitoring of positive and negative ions.

• High-Speed MRM Acquisition: Up to 5,000 MRM transitions/sec for multiplexed assays with no compromise on sensitivity.

• Dynamic Range: Spans 6+ orders of magnitude, enabling both trace-level and high-abundance compound analysis.

• Robust Design: LINAC® collision cell minimizes crosstalk and enhances reproducibility in complex biological or food matrices.

• Regulatory-Ready: Fully compliant with 21 CFR Part 11, GLP, and GMP laboratory standards.

• Software Ecosystem: SCIEX OS and Analyst® Software for advanced acquisition, processing, and reporting.

Applications:

• Pharmaceutical & Biopharma: Pharmacokinetics, drug metabolism (DMPK), impurity analysis, and bioequivalence studies.

• CRO Bioanalysis: High-throughput regulated LC-MS/MS workflows for clinical trial support.

• Food Safety & Agriculture: Ultra-trace detection of pesticides, mycotoxins, veterinary drugs, and contaminants.

• Environmental Analysis: Monitoring of trace pollutants, pharmaceuticals, and emerging contaminants in complex matrices.

• Clinical & Forensic Research: Therapeutic drug monitoring, forensic toxicology, and clinical pharmacology assays.

• Targeted Omics: Metabolomics and lipidomics requiring extreme sensitivity and robustness.

Specifications (Table):