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SCIEX Triple Quad 7500 LC-MS/MS System  ultra-sensitive, high-performance quantitative mass spectrometer for pharmaceutical bioanalysis, clinical toxicology, food safety, and environmental applications.

Key Features:

  • Most Sensitive SCIEX Triple Quad to Date: Provides up to 10× greater sensitivity compared to previous SCIEX Triple Quad systems, enabling ultra-trace detection.

  • Electronically Activated Orthogonal Accelerator (EAO): Improves ion focusing for enhanced sensitivity and stability.

  • OptiFlow® Source Technology: Enables seamless switching between high-flow and microflow applications for optimal flexibility.

  • SelexION+ Differential Ion Mobility (optional): Enhances selectivity by filtering out isobaric interferences before MS analysis.

  • Fast Polarity Switching: <5 ms switching ensures simultaneous monitoring of positive and negative ions.

  • Robust MRM Capability: Supports up to 5,000 MRM transitions/sec, ideal for complex multiplexed assays.

  • Ultra-Wide Dynamic Range: Covers 6+ orders of magnitude for simultaneous quantification of trace and abundant analytes.

  • High-Throughput Ready: Optimized for regulated bioanalytical and CRO environments with high sample volumes.

  • Enhanced Collision Cell: Redesigned LINAC® collision cell minimizes crosstalk and increases quantitative reproducibility.

  • Regulatory Compliance: Full support for 21 CFR Part 11, GLP/GMP environments.

  • Intelligent Software: SCIEX OS and Analyst® for compliant acquisition, streamlined workflows, and advanced reporting.


Applications:

  • Pharmaceutical & Biopharma: Pharmacokinetics, DMPK, metabolite quantitation, and impurity testing.

  • Clinical & Forensic Research: Therapeutic drug monitoring, toxicology, and clinical pharmacology assays.

  • Bioanalytical CROs: High-throughput quantitative analysis for drug development programs.

  • Food Safety & Agriculture: Detection of pesticide residues, mycotoxins, veterinary drugs, and contaminants at trace levels.

  • Environmental Testing: Ultra-trace quantitation of pollutants, pharmaceuticals, and emerging contaminants.

  • Targeted Omics: Highly sensitive metabolomics and lipidomics workflows.


Specifications (Table):

Parameter Specification
MS Type Triple Quadrupole LC-MS/MS
Mass Range m/z 5 – 2,000
Resolution Unit resolution (0.7 Da FWHM)
Polarity Switching <5 ms
Dynamic Range >6 orders of magnitude
MRM Transitions Up to 5,000 transitions/sec
Acquisition Modes MRM, Product Ion, Precursor Ion, Neutral Loss, Full Scan
Ionization Sources Turbo V™, OptiFlow® Turbo V, DuoSpray®, APCI
SelexION+ Technology Optional – Differential Ion Mobility
Collision Cell Enhanced LINAC® collision cell
Vacuum System Dual turbomolecular pumps
Software Analyst®, SCIEX OS
Compliance 21 CFR Part 11, GLP/GMP ready

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