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Key Features:
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Most Sensitive SCIEX Triple Quad to Date: Provides up to 10× greater sensitivity compared to previous SCIEX Triple Quad systems, enabling ultra-trace detection.
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Electronically Activated Orthogonal Accelerator (EAO): Improves ion focusing for enhanced sensitivity and stability.
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OptiFlow® Source Technology: Enables seamless switching between high-flow and microflow applications for optimal flexibility.
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SelexION+ Differential Ion Mobility (optional): Enhances selectivity by filtering out isobaric interferences before MS analysis.
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Fast Polarity Switching: <5 ms switching ensures simultaneous monitoring of positive and negative ions.
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Robust MRM Capability: Supports up to 5,000 MRM transitions/sec, ideal for complex multiplexed assays.
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Ultra-Wide Dynamic Range: Covers 6+ orders of magnitude for simultaneous quantification of trace and abundant analytes.
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High-Throughput Ready: Optimized for regulated bioanalytical and CRO environments with high sample volumes.
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Enhanced Collision Cell: Redesigned LINAC® collision cell minimizes crosstalk and increases quantitative reproducibility.
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Regulatory Compliance: Full support for 21 CFR Part 11, GLP/GMP environments.
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Intelligent Software: SCIEX OS and Analyst® for compliant acquisition, streamlined workflows, and advanced reporting.
Applications:
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Pharmaceutical & Biopharma: Pharmacokinetics, DMPK, metabolite quantitation, and impurity testing.
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Clinical & Forensic Research: Therapeutic drug monitoring, toxicology, and clinical pharmacology assays.
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Bioanalytical CROs: High-throughput quantitative analysis for drug development programs.
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Food Safety & Agriculture: Detection of pesticide residues, mycotoxins, veterinary drugs, and contaminants at trace levels.
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Environmental Testing: Ultra-trace quantitation of pollutants, pharmaceuticals, and emerging contaminants.
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Targeted Omics: Highly sensitive metabolomics and lipidomics workflows.
Specifications (Table):
| Parameter | Specification |
|---|---|
| MS Type | Triple Quadrupole LC-MS/MS |
| Mass Range | m/z 5 – 2,000 |
| Resolution | Unit resolution (0.7 Da FWHM) |
| Polarity Switching | <5 ms |
| Dynamic Range | >6 orders of magnitude |
| MRM Transitions | Up to 5,000 transitions/sec |
| Acquisition Modes | MRM, Product Ion, Precursor Ion, Neutral Loss, Full Scan |
| Ionization Sources | Turbo V™, OptiFlow® Turbo V, DuoSpray®, APCI |
| SelexION+ Technology | Optional – Differential Ion Mobility |
| Collision Cell | Enhanced LINAC® collision cell |
| Vacuum System | Dual turbomolecular pumps |
| Software | Analyst®, SCIEX OS |
| Compliance | 21 CFR Part 11, GLP/GMP ready |
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