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Shimadzu Nexera X3 UHPLC System – advanced high-throughput UHPLC platform with AI-driven performance monitoring, ultra-high pressure capacity, and regulatory compliance for pharmaceutical, proteomics, food safety, clinical, and environmental applications.
  • Shimadzu Nexera X3 UHPLC System – advanced high-throughput UHPLC platform with AI-driven performance monitoring, ultra-high pressure capacity, and regulatory compliance for pharmaceutical, proteomics, food safety, clinical, and environmental applications.
  • Shimadzu Nexera X3 UHPLC System – advanced high-throughput UHPLC platform with AI-driven performance monitoring, ultra-high pressure capacity, and regulatory compliance for pharmaceutical, proteomics, food safety, clinical, and environmental applications.
Shimadzu Nexera X3 UHPLC System
$0.00

  • Key Features:

    • The Shimadzu Nexera X3 UHPLC System is the latest-generation ultra-high-performance liquid chromatography platform, designed for maximum throughput, sensitivity, and robustness in demanding analytical environments.

    • Supports ultra-high pressure operation up to 130 MPa (18,850 psi), enabling use of sub-2 µm columns for superior resolution and fast separation times.

    • Delivers double the sample capacity of earlier models with high-speed autosamplers, optimized injection cycles, and enhanced cooling to maintain sample integrity.

    • Incorporates AI-driven performance monitoring and diagnostics, ensuring predictive maintenance, minimal downtime, and consistent reproducibility.

    • Offers flexible solvent delivery systems (binary, ternary, and quaternary gradient pumps) with ultra-precise flow rate and gradient accuracy.

    • Features advanced dual-heating column oven technology for stable and reproducible separations, even under demanding temperature gradients.

    • Integrates seamlessly with a wide range of detectors including PDA, fluorescence, RID, ELSD, and high-resolution mass spectrometers (Q-TOF, Orbitrap, triple quadrupole).

    • Controlled by Shimadzu LabSolutions CDS, ensuring regulatory compliance, full data integrity, and 21 CFR Part 11 electronic record/signature support.

    • Compact, modular, and scalable design suitable for standalone UHPLC or integrated LC/MS/MS workflows.

  • Applications:

    • Pharmaceutical & Biopharmaceutical: High-throughput drug screening, impurity profiling, QC release testing, biosimilar analysis, GMP-compliant workflows.

    • Proteomics & Metabolomics: Advanced peptide and protein separation, metabolite profiling, biomarker discovery.

    • Clinical & Biomedical Research: Bioanalysis of drugs, metabolites, hormones, and disease biomarkers.

    • Food & Nutraceuticals: Quality testing for vitamins, additives, preservatives, natural products, contaminants, and allergens.

    • Environmental Testing: Detection of pesticides, herbicides, endocrine disruptors, and trace pollutants.

    • Forensic & Toxicology: Ultra-sensitive analysis of drugs of abuse, toxins, and forensic markers.

    • Industrial Chemistry & Specialty Applications: Polymers, fine chemicals, process monitoring, and high-resolution purity assessments.

  • Specifications:

Parameter Specification
System Type Modular UHPLC platform
Pressure Rating Up to 130 MPa (18,850 psi)
Flow Rate Range 0.0001–5.0 mL/min
Pump Options Binary, ternary, and quaternary gradient pumps
Gradient Accuracy ±0.1% or better
Autosampler Ultra-fast cycle time, high sample capacity, injection range 0.1–100 µL, cooling/heating (4–40 °C), carryover <0.001%
Column Oven Ambient +4 °C to 90 °C, dual-heating system for precise thermal stability
Detector Options UV-Vis, PDA, fluorescence, RID, ELSD, MS integration (Q-TOF, Triple Quad, HRMS)
Software Shimadzu LabSolutions CDS (GLP/GMP and 21 CFR Part 11 compliant)
Throughput High sample throughput with parallel workflows and automated optimization
AI Functions Predictive diagnostics, auto-startup/shutdown, self-check routines
Carryover <0.001% (ultra-low carryover performance)
Dimensions Modular, stackable, optimized for lab space efficiency

 

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