Skip to product information
Shimadzu Nexera XR UHPLC System – compact, high-performance ultra-high-pressure liquid chromatography platform for pharmaceuticals, food safety, environmental testing, proteomics, and clinical research.
  • Key Features:

    • The Shimadzu Nexera XR UHPLC System is a high-performance, space-saving chromatography system designed for robust, reproducible, and high-throughput UHPLC analysis.

    • Supports pressures up to 66 MPa (9,600 psi), allowing use of sub-2 µm particle columns for improved resolution and reduced analysis time.

    • Delivers exceptional flow-rate accuracy and gradient precision, enabling reliable quantification in complex matrices.

    • Features an advanced quaternary gradient unit for flexibility in solvent mixing and gradient control.

    • Compact design ideal for labs with limited bench space while maintaining high performance and versatility.

    • Compatible with a wide range of detectors, including UV-Vis, PDA, RI, fluorescence, and mass spectrometry.

    • Integrated with Shimadzu LabSolutions software, offering intuitive control, full data integrity, and regulatory compliance (21 CFR Part 11).

    • Modular system architecture allows seamless upgrades to UHPLC-MS/MS workflows.

  • Applications:

    • Pharmaceuticals & Biopharmaceuticals: Drug development, stability testing, impurity profiling, dissolution testing, QC in GMP labs.

    • Proteomics & Metabolomics: High-resolution separation of peptides, proteins, amino acids, and metabolites.

    • Environmental Testing: Analysis of pesticides, endocrine disruptors, pollutants, and trace organics in water and soil.

    • Food & Beverage: Detection of vitamins, additives, aflatoxins, preservatives, and nutritional components.

    • Forensics & Toxicology: Screening of drugs, metabolites, and toxins.

    • Clinical & Biomedical Research: Biomarker quantification, hormone assays, bioanalytical method development.

    • Industrial Chemistry: Polymer analysis, specialty chemical purity, and process monitoring.

  • Specifications:

Parameter Specification
System Type Modular UHPLC system
Pressure Rating Up to 66 MPa (9,600 psi)
Flow Rate Range 0.0001–5.0 mL/min (high-precision control)
Pump Type Binary or quaternary gradient solvent delivery units
Gradient Accuracy ±0.35% or better
Autosampler High-precision injection (0.1–100 µL), low carryover, temperature control
Column Oven Temperature control: ambient +4 °C to 85 °C, column-switching capabilities
Detector Options UV-Vis, PDA, RID, fluorescence, mass spectrometer coupling
Software Shimadzu LabSolutions (GLP/GMP and 21 CFR Part 11 compliant)
Carryover <0.0025% (ultra-low carryover performance)
Dimensions Compact, stackable modules for space-saving integration


You may also like