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Key Features:
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The Shimadzu Nexera XR UHPLC System is a high-performance, space-saving chromatography system designed for robust, reproducible, and high-throughput UHPLC analysis.
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Supports pressures up to 66 MPa (9,600 psi), allowing use of sub-2 µm particle columns for improved resolution and reduced analysis time.
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Delivers exceptional flow-rate accuracy and gradient precision, enabling reliable quantification in complex matrices.
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Features an advanced quaternary gradient unit for flexibility in solvent mixing and gradient control.
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Compact design ideal for labs with limited bench space while maintaining high performance and versatility.
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Compatible with a wide range of detectors, including UV-Vis, PDA, RI, fluorescence, and mass spectrometry.
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Integrated with Shimadzu LabSolutions software, offering intuitive control, full data integrity, and regulatory compliance (21 CFR Part 11).
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Modular system architecture allows seamless upgrades to UHPLC-MS/MS workflows.
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Applications:
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Pharmaceuticals & Biopharmaceuticals: Drug development, stability testing, impurity profiling, dissolution testing, QC in GMP labs.
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Proteomics & Metabolomics: High-resolution separation of peptides, proteins, amino acids, and metabolites.
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Environmental Testing: Analysis of pesticides, endocrine disruptors, pollutants, and trace organics in water and soil.
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Food & Beverage: Detection of vitamins, additives, aflatoxins, preservatives, and nutritional components.
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Forensics & Toxicology: Screening of drugs, metabolites, and toxins.
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Clinical & Biomedical Research: Biomarker quantification, hormone assays, bioanalytical method development.
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Industrial Chemistry: Polymer analysis, specialty chemical purity, and process monitoring.
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Specifications:
| Parameter | Specification |
|---|---|
| System Type | Modular UHPLC system |
| Pressure Rating | Up to 66 MPa (9,600 psi) |
| Flow Rate Range | 0.0001–5.0 mL/min (high-precision control) |
| Pump Type | Binary or quaternary gradient solvent delivery units |
| Gradient Accuracy | ±0.35% or better |
| Autosampler | High-precision injection (0.1–100 µL), low carryover, temperature control |
| Column Oven | Temperature control: ambient +4 °C to 85 °C, column-switching capabilities |
| Detector Options | UV-Vis, PDA, RID, fluorescence, mass spectrometer coupling |
| Software | Shimadzu LabSolutions (GLP/GMP and 21 CFR Part 11 compliant) |
| Carryover | <0.0025% (ultra-low carryover performance) |
| Dimensions | Compact, stackable modules for space-saving integration |