Key Features:

• The Waters ACQUITY Bio Arc UPLC is a biopharma-optimized UPLC platform specifically engineered for protein, peptide, mAb, and biomolecule analysis.

• Equipped with the Waters 2998 Photodiode Array (PDA) Detector, providing full spectral scanning (190–800 nm) for peak purity analysis, structural confirmation, and monitoring of biomolecular stability.

• Features Arc Multi-flow path technology, enabling seamless method transfer from HPLC to UPLC without revalidation, ensuring reproducibility across analytical platforms.

• Designed with bio-inert flow paths to minimize sample interaction, carryover, and metal ion binding—critical for sensitive biomolecule separations.

• Compatible with Waters Protein-Pak, BEH, and other biopharma-focused UPLC columns for SEC, IEX, RP, and HILIC workflows.

• Operates at pressures up to 9,500 psi (≈ 660 bar) for high-resolution biomolecule separations.

• Integrated quaternary solvent delivery system supports complex gradients, including salt and pH-based bioseparations.

• Column oven with thermal stability ensures consistent peak shapes for temperature-sensitive biomolecules.

• Controlled by Waters Empower CDS, offering compliance-ready workflows with audit trails and full 21 CFR Part 11 support.

Applications:

• Biopharmaceutical Analysis: mAb characterization, peptide mapping, glycoprotein profiling, biosimilar comparability studies.

• Protein Chemistry: SEC for aggregation studies, RP for peptide analysis, IEX for charge variants.

• Pharmaceutical QC: Assay, stability, and impurity profiling of therapeutic proteins and peptides.

• Clinical Research: Biomarker analysis, proteomic screening, biotherapeutic monitoring.

• Food & Nutraceuticals: Protein and amino acid profiling, detection of bioactive peptides.

• Academic & Research Labs: Structural biology, biomolecule characterization, advanced separation science.

Specifications: