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Key Features:
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Proven Triple Quadrupole Design: Successor to the industry-standard API 4000™ with enhanced robustness and sensitivity.
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MRM Sensitivity: Capable of precise, reproducible targeted quantitation with low limits of detection.
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Fast Polarity Switching: <20 ms switching for workflows requiring both positive and negative ion monitoring.
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Dynamic MRM (dMRM): Optimizes cycle time and dwell time automatically for complex multi-analyte assays.
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Enhanced Ion Path: Improved ion optics and collision cell design for higher efficiency and signal-to-noise ratio.
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Wide Linear Dynamic Range: Suitable for quantitation of both trace-level and abundant analytes.
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Flexible Ion Sources: Compatible with Turbo V™ ion source, DuoSpray® source, and APCI for versatility across compound classes.
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Robust Throughput: Engineered for high-throughput targeted workflows with minimal downtime.
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21 CFR Part 11 Ready: Full compliance for regulated labs.
Applications:
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Pharmaceutical Research & QA/QC: Bioanalysis, PK/PD studies, and impurity profiling.
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Food & Beverage Testing: Pesticides, mycotoxins, veterinary drug residues, and contaminants.
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Environmental Analysis: Trace detection of pollutants and emerging contaminants in water, soil, and air.
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Clinical & Forensic Research: Drug screening, toxicology, and therapeutic drug monitoring.
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Biological Studies: Targeted proteomics and metabolomics with reproducible quantitative data.
Specifications (Table):
Parameter | Specification |
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MS Type | Triple Quadrupole LC-MS/MS |
Mass Range | m/z 5 – 2,000 |
Mass Resolution | Unit resolution (0.7 Da FWHM) |
Polarity Switching | <20 ms |
Dynamic Range | Linear over 5–6 orders of magnitude |
Acquisition Modes | MRM, Product Ion, Precursor Ion, Neutral Loss, Full Scan |
Ionization Sources | Turbo V™, DuoSpray®, APCI |
Scan Speed | Up to 5,000 Da/sec |
Collision Cell | Q2 with LINAC® collision cell technology |
Vacuum System | Dual turbomolecular pumps |
Software | Analyst® Software, optional SCIEX OS compatibility |
Compliance | 21 CFR Part 11, GLP/GMP ready |