Key Features:

• Hybrid Q-TOF Architecture: Quadrupole mass filter combined with high-resolution TOF analyzer for precise selection and accurate mass detection.

• Ultra-Sensitive Performance: Achieves sub-ppm mass accuracy with >30,000 FWHM resolution, ensuring reliable analyte identification.

• Eksigent nanoLC 425 Front-End: Nano-flow liquid chromatography with ultra-low flow precision and robustness, ideal for proteomics and biomarker studies.

• High-Speed Acquisition: >100 spectra/sec supports fast chromatography and large-scale proteomics workflows.

• SWATH DIA (Data-Independent Acquisition): Advanced SWATH capabilities provide deep, reproducible proteome and metabolome coverage across cohorts.

• Dynamic Range: >5 orders of magnitude for simultaneous analysis of low- and high-abundance molecules.

• Flexible Scan Modes: Full MS, IDA (Information Dependent Acquisition), MS/MSALL, SWATH DIA, and product ion scanning.

• Enhanced Proteomic Coverage: Optimized optics and electronics increase sensitivity compared to earlier models (e.g., 5600+).

• Fast Polarity Switching: <50 ms for efficient dual-mode ESI/APCI workflows.

• Software Ecosystem: SCIEX OS and Analyst® TF for acquisition, SWATH analysis, and regulatory compliance.

• Compliance Ready: Supports GLP/GMP standards with full 21 CFR Part 11 compliance for pharma/clinical labs.

Applications:

• Proteomics: Deep protein identification, large-cohort quantitative proteomics, biomarker discovery using SWATH DIA.

• Metabolomics & Lipidomics: Comprehensive profiling of small molecules and lipids in complex biological samples.

• Pharmaceutical Research: DMPK, impurity profiling, pharmacokinetics, and biopharma characterization.

• Clinical & Translational Research: Biomarker validation, disease pathway studies, and quantitative omics research.

• Food & Environmental Testing: High-resolution screening of pesticides, toxins, pollutants, and contaminants.

Specifications (Table):