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Agilent 1260 Infinity II GPC/SEC HPLC System with RI Detector modular chromatography platform for polymer and biopolymer molecular weight distribution and structural analysis in pharmaceutical, polymer, food, and research laboratories.
  • Key Features:

    • The Agilent 1260 Infinity II GPC/SEC System is a dedicated modular HPLC platform for polymer and biopolymer characterization.

    • Combines high-precision pumping, autosampler, thermostatted column compartment, and a high-sensitivity refractive index (RI) detector tailored for polymer applications.

    • Provides accurate molecular weight distribution determination and structural analysis of natural and synthetic polymers.

    • RI detector delivers exceptional baseline stability, low noise, and broad refractive index range, ideal for non-UV active analytes such as polymers.

    • Modular design allows flexible system configurations with additional detectors (UV, PDA, light scattering, viscometer).

    • Wide solvent compatibility ensures suitability for organic and aqueous GPC/SEC separations.

    • Fully integrated with Agilent OpenLab CDS software, supporting 21 CFR Part 11 compliance, data integrity, and audit trails.

    • System is optimized for robust, routine operation in QA/QC environments as well as advanced research.

    • Features excellent reproducibility with high-precision gradient formation and minimized delay volume.

  • Applications:

    • Polymer Industry: Molecular weight distribution of synthetic polymers, copolymers, and resins.

    • Biopolymers & Biopharma: Analysis of polysaccharides, glycoproteins, nucleic acids, and other biomacromolecules.

    • Pharmaceuticals: Formulation analysis of excipients, controlled-release polymers, PEGylated drugs.

    • Food & Nutrition: Carbohydrate and starch characterization.

    • Petrochemical Industry: Polymer additives, lubricants, and performance materials.

    • Academic & Research: Polymer chemistry, biopolymer structure studies, advanced SEC/GPC method development.

  • Specifications:

Parameter Specification
System Type Modular HPLC for GPC/SEC
Pressure Rating Up to 600 bar (8,700 psi)
Flow Rate Range 0.05–10.0 mL/min (precise flow control for polymer separations)
Pump Type Binary or quaternary gradient
Autosampler High precision, low carryover, variable injection volumes
Column Oven 4 °C above ambient to 85 °C with temperature stability ±0.1 °C
Detector High-sensitivity RI detector (baseline stability, wide refractive index range)
Additional Detector Options UV, PDA, multi-angle light scattering (MALS), viscometer
Software Agilent OpenLab CDS (GLP/GMP, 21 CFR Part 11 compliant)
Applications Molecular weight distribution, intrinsic viscosity, compositional analysis
Compliance GLP/GMP, 21 CFR Part 11

 

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