Key Features:

• Ultra-Sensitive Quantitation: Industry-leading LOQs for trace-level detection of small molecules, peptides, and metabolites.

• iFunnel Technology: Improved ion capture and transmission efficiency, delivering superior ion currents for high sensitivity.

• Dynamic Range: >6 orders of magnitude for quantitation of analytes across wide concentration ranges.

• Fast Polarity Switching: <20 ms switching between positive and negative modes in a single run.

• Advanced Collision Cell: LCID (linear collision cell with axial acceleration) for robust fragmentation and consistent quantitation.

• High Throughput Data Acquisition: Supports >500 MRM transitions/sec to match UHPLC peak capacity.

• Integrated with 1290 Infinity III UHPLC: State-of-the-art chromatography with up to 1300 bar pressure, ultra-low carryover, and superior injection precision.

• MRM & Dynamic MRM (dMRM): Reduces noise and increases robustness in complex sample workflows.

• Jet Stream ESI Source: Maximizes desolvation and ion focusing for better sensitivity and precision.

• Regulatory Compliance: Full 21 CFR Part 11 support for secure data handling in GMP/GLP laboratories.

• MassHunter Software Suite: Advanced quantitation, method optimization, compliance-ready reporting, and data integrity tools.

Applications:

• Pharmaceutical R&D and QA/QC: Pharmacokinetics, DMPK, impurity profiling, and clinical bioanalysis.

• Biopharmaceutical Analysis: Targeted peptide/protein quantitation, process monitoring, and stability studies.

• Food Safety: Trace detection of pesticides, veterinary drugs, mycotoxins, contaminants, and authenticity testing.

• Environmental Analysis: Emerging contaminants, endocrine disruptors, and pharmaceuticals in water, soil, and air.

• Clinical & Forensic Toxicology: Screening and quantitation of drugs of abuse, metabolites, and toxicants.

• Metabolomics & Lipidomics: Targeted quantitation of metabolites, lipids, and small molecules in biological research.

• Regulated Laboratory Workflows: Designed for GLP/GMP labs requiring validated reporting and compliance.

Specifications (Table):