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Key Features:
• Dedicated MALDI-TOF MS platform optimized for high-throughput drug discovery and screening workflows
• Ultra-fast data acquisition enabling label-free HTS (high-throughput screening) directly from 1536-well plates
• Smartbeam™ 3D laser with 10 kHz repetition rate for maximum speed and sensitivity
• True label-free detection, eliminating costly reagents and assay interference
• Automation-ready system with robotic integration for pharmaceutical screening environments
• Broad dynamic range for quantitative drug-target and drug–protein interaction studies
• Comprehensive software suite (PharmaPulse software) tailored for HTS assay analysis
• Scalable solution for primary, secondary, and tertiary drug discovery pipelines -
Applications:
• High-throughput screening (HTS) in pharmaceutical R&D
• Label-free drug-target interaction assays
• Screening of enzyme kinetics and inhibitor binding
• Profiling drug metabolism and compound libraries
• Biopharma development including antibody–drug conjugates (ADCs) and biologics screening
• Fragment-based drug discovery and hit validation -
Specifications:
Specification Details MS Platform Bruker rapifleX MALDI PharmaPulse MS System Type High-Throughput MALDI-TOF MS Ionization Source Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Analyzer Time-of-Flight (TOF) Mass Resolution High resolution with fast acquisition speed Laser Technology Smartbeam™ 3D 10 kHz laser for ultra-fast throughput Throughput 1536-well plate screening in minutes Dynamic Range Broad dynamic range suitable for quantitative assays Automation Full robotic integration for screening workflows Software Bruker PharmaPulse software suite with HTS assay tools Compliance 21 CFR Part 11 ready (for pharmaceutical and regulated labs)