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PerkinElmer QSight 420 Triple Quadrupole LC-MS/MS with LX50 UHPLC high-sensitivity, robust targeted mass spectrometry system for food safety, environmental, pharmaceutical, and clinical toxicology applications.
  • PerkinElmer QSight 420 Triple Quadrupole LC-MS/MS with LX50 UHPLC high-sensitivity, robust targeted mass spectrometry system for food safety, environmental, pharmaceutical, and clinical toxicology applications.
  • PerkinElmer QSight 420 Triple Quadrupole LC-MS/MS with LX50 UHPLC high-sensitivity, robust targeted mass spectrometry system for food safety, environmental, pharmaceutical, and clinical toxicology applications.
PerkinElmer QSight 420 Triple Quadrupole LC/MS/MS with LX50 UHPLC Front End
$0.00

Key Features:

  • Triple Quadrupole Technology: High-sensitivity and selectivity for quantitative targeted LC-MS/MS workflows.

  • QSight 420 MS Performance: Provides robust, reproducible quantitation with excellent signal-to-noise ratios for trace-level detection.

  • Integrated LX50 UHPLC System: Fast, precise, and reliable liquid chromatography delivering sharp peak resolution and reproducible gradients.

  • Dual Source Design: Incorporates ESI (Electrospray Ionization) and APCI (Atmospheric Pressure Chemical Ionization) for broad analyte coverage.

  • Stability & Uptime: Known for exceptional robustness, minimal maintenance downtime, and extended continuous operation.

  • Dynamic Range: Wide linear range to quantify both high- and low-abundance analytes.

  • Fast Polarity Switching: Supports rapid transitions between positive and negative ion modes within a single run.

  • Quantitation Focused: Optimized for high-throughput targeted workflows, particularly in regulated environments.

  • Software Ecosystem: Simplicity™ 3Q for streamlined acquisition, data processing, and regulatory compliance reporting.

  • Compliance Ready: Meets FDA 21 CFR Part 11 and supports GLP/GMP workflows.

Applications:

  • Food Safety & Agriculture: Quantification of pesticide residues, mycotoxins, veterinary drugs, food contaminants.

  • Environmental Testing: Analysis of emerging pollutants, pharmaceuticals in water, and soil contaminants.

  • Pharmaceutical & Biopharma: Targeted drug bioanalysis, impurity quantitation, pharmacokinetics.

  • Clinical & Forensic Toxicology: Routine targeted drug screening, toxicological confirmation, biomarker analysis.

  • Industrial & Contract Testing Labs: High-throughput targeted LC-MS/MS workflows requiring reliability and reproducibility.

Specifications (Table):

Parameter Specification
System Configuration PerkinElmer QSight 420 Triple Quad LC-MS/MS + LX50 UHPLC
MS Type Triple Quadrupole Mass Spectrometer
Mass Range m/z ~10 – 2000
Resolution Unit resolution (0.7 Da FWHM)
Dynamic Range 5–6 orders of magnitude
Ionization Modes Dual Ion Source (ESI, APCI)
Polarity Switching <50 ms
Acquisition Modes MRM, SIM, Product Ion
MRM Transition Speed High-speed transitions for UHPLC peaks
Sensitivity (LOQ) fg–pg range (compound dependent)
Collision Cell High-efficiency collision cell with optimized gas flow
Vacuum System Turbo molecular pump system
Front-End UHPLC PerkinElmer LX50 UHPLC (binary/quaternary pumps, autosampler, column oven, detectors)
Autosampler LX50 autosampler, low carryover, precision injections
Flow Range 0.001 – 10 mL/min (pump dependent)
Gradient Precision ≤0.1% RSD
Interface Dual ion source with orthogonal spray
Software Simplicity™ 3Q for MS control, quantitation, reporting
Compliance 21 CFR Part 11, GLP/GMP ready



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