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SCIEX QTRAP 3200 LC-MS/MS with Agilent 1260 Infinity II HPLC hybrid triple quadrupole linear ion trap system for versatile quantitative and qualitative LC-MS/MS workflows in pharma, food safety, clinical, and environmental labs.

Key Features:

  • Hybrid QTRAP Technology: Combines triple quadrupole quantitation with linear ion trap functionality for both targeted and qualitative workflows.

  • Enhanced Product Ion (EPI) Scanning: Allows structural elucidation of metabolites and unknown compounds.

  • Triple Quad Performance: Highly sensitive MRM mode ensures precise quantitation at low levels.

  • MS³ Capability: Linear ion trap supports advanced fragmentation studies beyond MS/MS.

  • Fast Polarity Switching: <50 ms for efficient positive/negative ion detection in a single run.

  • Agilent 1260 Infinity II HPLC Front-End: Delivers precise, reproducible chromatographic separations with up to 600 bar pressure and advanced diode array detection options.

  • Dynamic MRM: Handles large panels of analytes without compromising sensitivity or reproducibility.

  • Compact, Cost-Effective Platform: Designed as an affordable yet powerful LC-MS/MS system for versatile laboratory needs.

  • Regulatory-Ready: Fully supports 21 CFR Part 11 compliance for regulated bioanalysis.

  • Analyst® Software Integration: Comprehensive control, quantitation, and reporting with secure workflows.


Applications:

  • Pharmaceutical & Biopharma: DMPK, pharmacokinetics, bioanalysis, impurity profiling.

  • Food Safety: Detection of pesticide residues, mycotoxins, veterinary drugs, and food contaminants.

  • Environmental Analysis: Monitoring pollutants, pharmaceuticals, and industrial chemicals.

  • Clinical & Forensic Toxicology: Drug screening, forensic toxicology, biomarker quantitation.

  • Metabolomics: Targeted metabolite profiling and structural elucidation.

  • Academic Research: Structural characterization and flexible quantitative/qualitative workflows.


Specifications (Table):

Parameter Specification
System Configuration SCIEX QTRAP 3200 LC-MS/MS with Agilent 1260 Infinity II HPLC
MS Type Hybrid Triple Quadrupole – Linear Ion Trap (QTRAP)
Mass Range m/z 5 – 2000
Resolution Unit mass resolution (0.7 Da FWHM)
Dynamic Range 4–5 orders of magnitude
Ionization Modes Turbo V™ source with ESI and APCI options
Polarity Switching <50 ms
Acquisition Modes MRM, SIM, Enhanced Product Ion (EPI), MS³, Precursor Ion Scan, Neutral Loss Scan
MRM Transition Speed Up to 300 transitions/sec
Sensitivity (LOQ) Low pg to fg level (compound dependent)
Collision Cell Q2 linear collision cell
Vacuum System Advanced turbomolecular pumping system
HPLC System Agilent 1260 Infinity II (up to 600 bar, high-precision quaternary pump, DAD options)
Autosampler Integrated 1260 Infinity II autosampler with low carryover
Interface Turbo V ion source with orthogonal spray design
Software SCIEX Analyst® software
Compliance 21 CFR Part 11, GLP/GMP ready


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