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SCIEX QTRAP 4500 LC-MS/MS with Agilent 1260 Infinity II HPLC hybrid triple quadrupole linear ion trap UHPLC-MS/MS system for high-sensitivity quantitation and qualitative analysis in pharmaceuticals, food safety, clinical toxicology, and environmental testing.
  • SCIEX QTRAP 4500 LC-MS/MS with Agilent 1260 Infinity II HPLC hybrid triple quadrupole linear ion trap UHPLC-MS/MS system for high-sensitivity quantitation and qualitative analysis in pharmaceuticals, food safety, clinical toxicology, and environmental testing.
  • SCIEX QTRAP 4500 LC-MS/MS with Agilent 1260 Infinity II HPLC hybrid triple quadrupole linear ion trap UHPLC-MS/MS system for high-sensitivity quantitation and qualitative analysis in pharmaceuticals, food safety, clinical toxicology, and environmental testing.
SCIEX QTRAP 4500 LC-MS/MS with Agilent 1260 Infinity II HPLC
$0.00

Key Features:

  • Hybrid QTRAP Technology: Combines triple quadrupole quantitation with linear ion trap scanning for both targeted quantitation and qualitative structural analysis.

  • Agilent 1260 Infinity II HPLC Front-End: Provides UHPLC compatibility, excellent chromatographic resolution, precise flow control, and efficient gradient delivery.

  • High-Speed Quantitation: Up to 1000 MRM transitions/sec, supporting fast UHPLC separations with narrow peaks.

  • Polarity Switching: <50 ms for simultaneous detection of analytes in both positive and negative ionization modes.

  • Enhanced Product Ion (EPI) and MS³ Capability: Allows structural elucidation, metabolite identification, and confirmation of unknowns.

  • Turbo V™ Source with ESI/APCI Options: Delivers stable and efficient ionization across a wide compound range.

  • Compact Design: Space-saving mass spectrometer combined with modular Agilent HPLC, making it a versatile benchtop solution.

  • Software Ecosystem: SCIEX Analyst® and MultiQuant™ for acquisition and quantitation, fully compliant with GLP/GMP and 21 CFR Part 11.

  • Reliability & Versatility: Ideal for labs that require robust quantitation with qualitative confirmation in regulated and research workflows.

Applications:

  • Pharmaceutical & Biopharma: Bioanalytical assays, DMPK studies, metabolite ID, impurity profiling.

  • Food Safety & Agriculture: Detection and quantitation of pesticide residues, mycotoxins, veterinary drug residues.

  • Environmental Analysis: Pollutant monitoring, trace pharmaceuticals, endocrine disruptors in water/soil.

  • Clinical & Forensic Toxicology: Targeted drug screening, forensic toxicology, biomarker quantitation.

  • Metabolomics & Lipidomics: Targeted quantitation with confirmatory EPI scans for pathway studies.

  • Academic & Translational Research: Versatile platform for method development, quantitative studies, and structural elucidation.

Specifications (Table):

Parameter Specification
System Configuration SCIEX QTRAP 4500 LC-MS/MS + Agilent 1260 Infinity II HPLC
MS Type Hybrid Triple Quadrupole – Linear Ion Trap (QTRAP)
Mass Range m/z 5 – 2000
Resolution Unit resolution (0.7 Da FWHM)
Dynamic Range ~5 orders of magnitude
Ionization Modes Turbo V™ Source (ESI, APCI)
Polarity Switching <50 ms
Acquisition Modes MRM, SIM, EPI, MS³, Precursor Ion, Neutral Loss Scan
MRM Transition Speed Up to 1000 transitions/sec
Sensitivity (LOQ) fg–pg level (compound dependent)
Collision Cell Q2 linear collision cell
Vacuum System Turbo molecular pump system
Front-End HPLC Agilent 1260 Infinity II HPLC (binary/quaternary pumps, autosampler, DAD/UV detectors, column oven)
Autosampler Agilent 1260 Infinity II multisampler
Flow Range 0.001 – 10 mL/min (depending on pump configuration)
Gradient Precision ≤ 0.05% RSD
Interface Turbo V ion source with orthogonal spray
Software SCIEX Analyst®, MultiQuant™ (MS); Agilent ChemStation/Chromeleon (HPLC)
Compliance 21 CFR Part 11, GLP/GMP ready


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