Key Features:

• Hybrid QTRAP Technology: Combines triple quadrupole MRM quantitation with linear ion trap for enhanced qualitative workflows.

• Ultra-Sensitive Quantitation: fg-level limits of detection and quantitation for challenging trace-level compounds.

• Fast Polarity Switching: <5 ms switching between positive and negative modes for multi-analyte assays.

• High-Speed MRM Performance: Up to 30,000 transitions per second for large-scale targeted bioanalysis.

• Scheduled MRM™ Pro & MRM³: Reduces cycle times while improving selectivity and sensitivity.

• SelexION®+ (optional): Differential mobility separation adds orthogonal selectivity for complex samples.

• Turbo V™ Source with Stable Ion Drive: Improved ionization efficiency and ruggedness for extended uptime.

• Shimadzu Nexera UHPLC: Delivers high-throughput chromatography with excellent reproducibility, sub-2 μm particle compatibility, and ultra-fast gradients.

• Dynamic Range: Wide linear range of >6 orders of magnitude, enabling simultaneous quantitation of low- and high-abundance analytes.

• Regulatory Compliance: Supports 21 CFR Part 11, GLP, and GMP environments for regulated bioanalytical labs.

• Software Ecosystem: SCIEX OS for integrated control, data acquisition, quantitative processing, and reporting.

Applications:

• Pharmaceutical & Bioanalytical: High-throughput PK/PD studies, drug metabolism, DMPK, bioequivalence testing.

• Clinical Research & Toxicology: Quantification of drugs, metabolites, therapeutic monitoring, forensic toxicology.

• Food & Environmental Testing: High-sensitivity screening of pesticides, veterinary residues, pollutants, mycotoxins.

• Proteomics & Metabolomics: Targeted biomarker verification, quantitative metabolite profiling.

• Biotherapeutics Development: Targeted peptide, protein, and oligonucleotide quantitation in complex matrices.

Specifications (Table):