Key Features:
• Latest generation of Thermo’s Tribrid™ architecture with enhanced sensitivity, dynamic range, and intelligent acquisition
• Incorporates multi-omics capability, enabling deeper insights across proteomics, metabolomics, lipidomics, and glycomics in a single platform
• Improved ion transmission and optics for higher signal-to-noise ratio and robust reproducibility
• Advanced fragmentation technologies: CID, HCD, ETD, EThcD, UVPD, with enhanced efficiency for PTM analysis
• Supports real-time search (RTS) for deeper proteomic coverage and faster identifications
• Expanded compatibility with TMT multiplexing workflows for high-throughput quantitative studies
• Optimized for biopharma applications, including intact protein analysis, mAbs, ADCs, and peptide mapping
• Seamless integration with UHPLC, nanoLC, and FAIMS Pro™ ion mobility interface for improved selectivity
• Software ecosystem: Xcalibur™, Proteome Discoverer™, Biopharma Finder™, Chromeleon™, and deep learning-enabled workflows
• Full compliance with regulatory environments (21 CFR Part 11 ready)

Applications:
• Large-scale proteomics and quantitative biomarker discovery
• PTM mapping (phosphorylation, glycosylation, ubiquitination, acetylation)
• Metabolomics, lipidomics, and glycomics research
• Biopharmaceutical development, including intact protein and top-down analysis
• Multi-omics workflows integrating proteomics, metabolomics, and lipidomics
• Structural biology and systems biology studies

Specifications: