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Key Features:
• Enhanced Quadrupole-Orbitrap HRAM design with improved ion optics and higher sensitivity over the standard Q Exactive
• Resolution up to 280,000 FWHM at m/z 200 with <1 ppm mass accuracy
• Superior quantitative performance for complex proteomic and metabolomic samples
• Fast polarity switching and higher scan rates for large-scale omics datasets
• Optimized HCD fragmentation for confident PTM and structural elucidation
• Robust integration with UltiMate 3000 UHPLC for high-throughput, reproducible separations
• Expanded dynamic range and linearity suitable for discovery and targeted workflows
• Intuitive software solutions with advanced data analysis for omics and biopharma research
• Compact benchtop system delivering reliability and performance for demanding applications -
Applications:
• Proteomics: Deep protein identification, quantification, and PTM mapping
• Metabolomics & Lipidomics: High-resolution profiling of metabolites and lipids
• Biopharma: Peptide mapping, intact protein characterization, and glycan analysis
• Food Safety & Environmental: Screening of contaminants and trace-level analytes
• Clinical & Translational Research: Quantitative biomarker discovery and validation -
Specifications:
Specification Details MS Platform Thermo Scientific Q Exactive Plus Orbitrap MS System Type Hybrid Quadrupole-Orbitrap LC-MS/MS Coupled System Thermo Scientific UltiMate 3000 UHPLC Ionization Source Electrospray Ionization (ESI), nano-ESI Mass Analyzers Quadrupole + Orbitrap Mass Resolution Up to 280,000 FWHM at m/z 200 Mass Accuracy <1 ppm with external calibration Fragmentation Methods Higher-energy Collisional Dissociation (HCD) Polarity Modes Positive and negative ion switching Dynamic Range >5 orders of magnitude Sensitivity Sub-femtomole detection sensitivity Acquisition Modes Full MS, MS/MS, PRM, DIA Software Thermo Xcalibur™, TraceFinder™, Proteome Discoverer™ Compliance 21 CFR Part 11 ready