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Key Features:
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High-performance Triple Quadrupole LC-MS/MS for reliable, ultra-sensitive quantitation across complex matrices
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Integrated UltiMate 3000 UHPLC for robust and flexible chromatographic separations with high throughput
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Advanced ion optics and collision cell design for maximum sensitivity and reproducibility
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Rapid polarity switching (<5 ms) supports broad multi-analyte workflows
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Wide linear dynamic range (>6 orders of magnitude) for simultaneous trace and high-concentration analysis
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Exceptional signal-to-noise performance enabling detection of low-abundance analytes
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TraceFinder and Xcalibur software provide streamlined acquisition, quantitation, and compliance-ready reporting
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Applications:
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Pharmaceuticals: Drug development, pharmacokinetics, metabolite quantitation, impurity profiling
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Food Safety: Residue monitoring of pesticides, veterinary drugs, contaminants
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Environmental Analysis: Detection of pollutants, endocrine disruptors, emerging contaminants
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Clinical Research: Quantitative biomarker assays, therapeutic drug monitoring, toxicology
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Forensic Analysis: Screening and quantitation of drugs and toxicants
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Specifications:
| Specification | Detail |
|---|---|
| LC/MS Platform | TSQ Altis Triple Quadrupole LC-MS/MS with UltiMate 3000 UHPLC |
| MS System Type | Triple Quadrupole |
| Mass Range | m/z 10–2,000 |
| Ionization Modes | ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional |
| Autosampler | UltiMate 3000 UHPLC autosampler with temperature control |
| Acquisition Modes | Full Scan, SIM, MRM (Multiple Reaction Monitoring), Quantitative MS/MS |
| Dynamic Range | >6 orders of magnitude |
| Mass Accuracy | Unit mass resolution (Q1/Q3 quadrupoles) |
| Scan Speed | >600 MRM transitions/sec |
| Vacuum System | Dual turbomolecular pumps with backing pump |
| Interface | HESI-II heated electrospray source, optional APCI |
| Software | Thermo Scientific TraceFinder, Xcalibur, Chromeleon |
| Compliance | 21 CFR Part 11 compatible |