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Thermo Scientific TSQ Endura Triple Quadrupole LC-MS/MS with Vanquish UHPLC robust quantitative LC-MS system for pharmaceutical, food safety, environmental, and clinical testing applications
  • Key Features:

    • Proven Triple Quadrupole LC-MS/MS platform designed for reliable, routine quantitation

    • Integrated Vanquish UHPLC delivers high-resolution separations and efficient sample throughput

    • Robust ion optics and collision cell design provide stable, reproducible performance across diverse sample types

    • Fast polarity switching (<5 ms) enables flexible multi-residue or multi-class analysis

    • Wide linear dynamic range (>5 orders of magnitude) for both trace detection and higher-level quantitation

    • Simplified, rugged design for long-term operational reliability and minimal downtime

    • TraceFinder software ensures intuitive quantitation, streamlined workflows, and compliance support

  • Applications:

    • Pharmaceuticals: Drug metabolism studies, pharmacokinetics, impurity testing

    • Food Safety: Detection of pesticides, veterinary drugs, and contaminants

    • Environmental Testing: Monitoring pollutants, POPs, and emerging contaminants

    • Clinical Research: Quantitative assays, therapeutic drug monitoring, biomarker analysis

    • Forensic/Toxicology: Routine quantitation of drugs and toxicants

  • Specifications:

Specification Detail
LC/MS Platform TSQ Endura Triple Quadrupole LC-MS/MS with Vanquish UHPLC
MS System Type Triple Quadrupole
Mass Range m/z 10–2,000
Ionization Modes ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional
Autosampler Vanquish UHPLC autosampler with precise injection and temperature control
Acquisition Modes Full Scan, SIM, MRM (Multiple Reaction Monitoring)
Dynamic Range >5 orders of magnitude
Mass Accuracy Unit mass resolution (Q1/Q3 quadrupoles)
Scan Speed Up to ~500 MRM transitions/sec
Vacuum System Dual turbomolecular pumps with forepump
Interface HESI-II heated electrospray source, optional APCI
Software Thermo Scientific TraceFinder, Xcalibur, Chromeleon
Compliance 21 CFR Part 11 compatible

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