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Key Features:
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Proven Triple Quadrupole LC-MS/MS platform designed for reliable, routine quantitation
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Integrated Vanquish UHPLC delivers high-resolution separations and efficient sample throughput
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Robust ion optics and collision cell design provide stable, reproducible performance across diverse sample types
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Fast polarity switching (<5 ms) enables flexible multi-residue or multi-class analysis
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Wide linear dynamic range (>5 orders of magnitude) for both trace detection and higher-level quantitation
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Simplified, rugged design for long-term operational reliability and minimal downtime
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TraceFinder software ensures intuitive quantitation, streamlined workflows, and compliance support
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Applications:
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Pharmaceuticals: Drug metabolism studies, pharmacokinetics, impurity testing
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Food Safety: Detection of pesticides, veterinary drugs, and contaminants
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Environmental Testing: Monitoring pollutants, POPs, and emerging contaminants
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Clinical Research: Quantitative assays, therapeutic drug monitoring, biomarker analysis
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Forensic/Toxicology: Routine quantitation of drugs and toxicants
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Specifications:
| Specification | Detail |
|---|---|
| LC/MS Platform | TSQ Endura Triple Quadrupole LC-MS/MS with Vanquish UHPLC |
| MS System Type | Triple Quadrupole |
| Mass Range | m/z 10–2,000 |
| Ionization Modes | ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional |
| Autosampler | Vanquish UHPLC autosampler with precise injection and temperature control |
| Acquisition Modes | Full Scan, SIM, MRM (Multiple Reaction Monitoring) |
| Dynamic Range | >5 orders of magnitude |
| Mass Accuracy | Unit mass resolution (Q1/Q3 quadrupoles) |
| Scan Speed | Up to ~500 MRM transitions/sec |
| Vacuum System | Dual turbomolecular pumps with forepump |
| Interface | HESI-II heated electrospray source, optional APCI |
| Software | Thermo Scientific TraceFinder, Xcalibur, Chromeleon |
| Compliance | 21 CFR Part 11 compatible |