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Key Features:
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Triple quadrupole LC-MS/MS system optimized for reliable, high-throughput quantitation
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Integrated Vanquish UHPLC for superior chromatographic resolution and reproducibility
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Robust, compact design ideal for routine laboratory workflows with minimal downtime
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Fast polarity switching for multi-analyte methods within a single run
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Optimized ion optics for high sensitivity and reproducibility in demanding applications
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Wide linear dynamic range supporting both trace-level detection and high-concentration samples
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Compliance-ready software solutions ensuring 21 CFR Part 11 compatibility
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Applications:
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Pharmaceutical analysis: Drug quantitation, bioequivalence, impurity and metabolite studies
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Food safety: Pesticide residues, veterinary drugs, contaminants monitoring
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Environmental testing: Trace pollutants, endocrine disruptors, organic contaminants
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Clinical research: Quantitative biomarker assays, therapeutic drug monitoring
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Forensics and toxicology: Drugs of abuse, toxicant detection in biological samples
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Specifications:
| Specification | Detail |
|---|---|
| LC/MS Platform | TSQ Fortis Triple Quadrupole LC-MS/MS with Vanquish UHPLC |
| MS System Type | Triple Quadrupole |
| Mass Range | m/z 10–2,000 |
| Ionization Modes | ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional |
| Autosampler | Thermo Scientific Vanquish UHPLC Autosampler |
| Acquisition Modes | Full Scan, SIM, MRM (Multiple Reaction Monitoring), Quantitative MS/MS |
| Dynamic Range | >5 orders of magnitude |
| Mass Accuracy | Unit mass resolution in Q1 and Q3 quadrupoles |
| Scan Speed | Up to 500 MRM transitions/sec |
| Vacuum System | Dual turbomolecular pumps with forepump |
| Interface | HESI-II heated electrospray source, optional APCI |
| Software | Thermo Scientific TraceFinder, Xcalibur, and Chromeleon software |
| Compliance | 21 CFR Part 11 compatible |