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Key Features:
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High-performance Triple Quadrupole LC-MS/MS designed for advanced quantitative analysis
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Integrated Vanquish UHPLC ensures sharp peaks, fast separations, and excellent reproducibility
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S-Lens ion optics improve ion transmission efficiency and sensitivity across a wide mass range
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Fast polarity switching (<5 ms) enables complex, multi-class methods without delay
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High sensitivity and low detection limits ideal for trace-level quantitation in complex matrices
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Wide linear dynamic range (>5–6 orders of magnitude) supports both trace and bulk quantification
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Robust engineering ensures long-term stability and reduced downtime in demanding laboratories
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Xcalibur and TraceFinder software streamline data acquisition, quantitation, and compliance
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Applications:
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Pharmaceuticals: Bioanalysis, pharmacokinetics, drug development, impurity profiling
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Food Safety: Detection of pesticides, veterinary drugs, mycotoxins, and contaminants
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Environmental Testing: Monitoring persistent organic pollutants, water contaminants, and endocrine disruptors
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Clinical Research: Quantitative biomarker assays, therapeutic drug monitoring
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Forensics/Toxicology: Screening and quantitation of drugs of abuse and toxicants
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Specifications:
| Specification | Detail |
|---|---|
| LC/MS Platform | TSQ Vantage Triple Quadrupole LC-MS/MS with Vanquish UHPLC |
| MS System Type | Triple Quadrupole |
| Mass Range | m/z 10–2,000 |
| Ionization Modes | ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional |
| Autosampler | Vanquish UHPLC autosampler with precise injection and temperature control |
| Acquisition Modes | Full Scan, SIM, MRM (Multiple Reaction Monitoring) |
| Dynamic Range | >5–6 orders of magnitude |
| Mass Accuracy | Unit mass resolution (Q1/Q3 quadrupoles) |
| Scan Speed | Up to ~500+ MRM transitions/sec |
| Vacuum System | Dual turbomolecular pumps with forepump |
| Interface | HESI-II heated electrospray source, optional APCI |
| Software | Thermo Scientific Xcalibur, TraceFinder, Chromeleon |
| Compliance | 21 CFR Part 11 compatible |