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Thermo Scientific TSQ Vantage Triple Quadrupole LC-MS/MS with Vanquish UHPLC high-sensitivity quantitative LC-MS/MS system for pharmaceutical, food safety, environmental, and clinical applications
  • Key Features:

    • High-performance Triple Quadrupole LC-MS/MS designed for advanced quantitative analysis

    • Integrated Vanquish UHPLC ensures sharp peaks, fast separations, and excellent reproducibility

    • S-Lens ion optics improve ion transmission efficiency and sensitivity across a wide mass range

    • Fast polarity switching (<5 ms) enables complex, multi-class methods without delay

    • High sensitivity and low detection limits ideal for trace-level quantitation in complex matrices

    • Wide linear dynamic range (>5–6 orders of magnitude) supports both trace and bulk quantification

    • Robust engineering ensures long-term stability and reduced downtime in demanding laboratories

    • Xcalibur and TraceFinder software streamline data acquisition, quantitation, and compliance

  • Applications:

    • Pharmaceuticals: Bioanalysis, pharmacokinetics, drug development, impurity profiling

    • Food Safety: Detection of pesticides, veterinary drugs, mycotoxins, and contaminants

    • Environmental Testing: Monitoring persistent organic pollutants, water contaminants, and endocrine disruptors

    • Clinical Research: Quantitative biomarker assays, therapeutic drug monitoring

    • Forensics/Toxicology: Screening and quantitation of drugs of abuse and toxicants

  • Specifications:

Specification Detail
LC/MS Platform TSQ Vantage Triple Quadrupole LC-MS/MS with Vanquish UHPLC
MS System Type Triple Quadrupole
Mass Range m/z 10–2,000
Ionization Modes ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional
Autosampler Vanquish UHPLC autosampler with precise injection and temperature control
Acquisition Modes Full Scan, SIM, MRM (Multiple Reaction Monitoring)
Dynamic Range >5–6 orders of magnitude
Mass Accuracy Unit mass resolution (Q1/Q3 quadrupoles)
Scan Speed Up to ~500+ MRM transitions/sec
Vacuum System Dual turbomolecular pumps with forepump
Interface HESI-II heated electrospray source, optional APCI
Software Thermo Scientific Xcalibur, TraceFinder, Chromeleon
Compliance 21 CFR Part 11 compatible

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