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Waters ACQUITY APC System  advanced polymer chromatography solution for high-resolution size exclusion chromatography, enabling accurate polymer molecular weight and structural analysis in research and quality control.
  • Key Features:

    • Waters ACQUITY APC system is a next-generation high-resolution polymer chromatography platform specifically designed for rapid and accurate size exclusion chromatography (SEC) of polymers and macromolecules.

    • Utilizes sub-3 µm and sub-2 µm particle size APC columns, providing higher resolution, shorter run times, and improved separation efficiency compared to traditional GPC/SEC systems.

    • Optimized for both aqueous and organic solvent applications, making it versatile for synthetic polymers, biopolymers, and specialty materials.

    • Delivers robust system pressure handling, enabling the use of shorter columns without loss of resolution, reducing solvent consumption and analysis cost.

    • Compatible with multiple detectors including Refractive Index (RI), Photodiode Array (PDA), UV/Vis, and Multi-Angle Light Scattering (MALS) for advanced molecular weight characterization.

    • Seamlessly integrates with Waters Empower™ GPC/SEC software, supporting molecular weight averages, polydispersity, branching, intrinsic viscosity, and other advanced calculations.

    • Ensures excellent reproducibility and compliance with GLP/GMP and 21 CFR Part 11 regulatory requirements.

    • Designed for high-throughput polymer analysis labs, providing efficiency, accuracy, and robustness.

  • Applications:

    • Polymer Industry: Fast molecular weight distribution profiling of resins, plastics, elastomers, and engineered polymers.

    • Biopolymers: Analysis of polysaccharides, cellulose derivatives, PEGs, and other bio-based macromolecules.

    • Pharmaceuticals: Characterization of excipients, polymer-based drug carriers, and PEGylated compounds.

    • Food & Nutrition: SEC of starches, gums, hydrocolloids, and polysaccharides.

    • Specialty & Advanced Materials: Nanomaterials, block copolymers, biodegradable plastics.

    • Research & Academia: Advanced studies in polymer chemistry, biomaterials, and nanotechnology.

  • Specifications:

Parameter Specification
System Type Advanced Polymer Chromatography (APC) for high-resolution SEC
Pump Binary solvent delivery, high-pressure capable
Flow Rate Range 0.001–2 mL/min (UHPLC-grade flow precision)
Pressure Rating Up to 15,000 psi (supports APC sub-2 µm columns)
Autosampler High-capacity with precise injection reproducibility
Column Technology Sub-3 µm and sub-2 µm particle APC columns
Detector Options RI, PDA, UV/Vis, Light Scattering (MALS), Viscometer
Software Waters Empower GPC/SEC with advanced polymer calculations
Applications Molecular weight, polydispersity, branching, intrinsic viscosity
Compliance GLP/GMP, 21 CFR Part 11


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