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Key Features:
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Multi-Reflecting Time-of-Flight (MRT) technology delivering ultra-high resolution and mass accuracy.
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Resolution exceeding 200,000 FWHM, enabling fine isotopic separation and confident analyte identification.
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Extended flight path MRT analyzer increases resolution without sacrificing sensitivity or duty cycle.
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Seamlessly integrated with ACQUITY UPLC for high-efficiency separations.
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High dynamic range and sensitivity suitable for complex biological, pharmaceutical, and environmental samples.
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Compatible with ion mobility separation (IMS) workflows for multidimensional molecular characterization.
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Fully supported by UNIFI scientific information system for compliance, reporting, and streamlined analysis.
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Applications:
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Proteomics: High-resolution peptide mapping, PTM characterization, biomarker discovery.
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Metabolomics & Lipidomics: Untargeted small molecule profiling, structural elucidation.
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Biopharmaceuticals: Intact mass analysis, glycosylation profiling, impurity/degradation studies.
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Pharmaceutical Development: Drug metabolism studies, impurity characterization, lead optimization.
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Environmental & Food Safety: High-resolution screening of trace contaminants and residues.
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Specifications:
| Specification | Detail |
|---|---|
| LC/MS Platform | Waters SELECT SERIES MRT LC-MS with ACQUITY UPLC |
| MS System Type | Multi-Reflecting Time-of-Flight (MRT) Hybrid |
| Mass Range | m/z 20–100,000 |
| Resolution | >200,000 FWHM |
| Ionization Modes | ESI, NanoESI, APCI, APPI optional |
| Autosampler | ACQUITY UPLC autosampler |
| Acquisition Modes | MS, MS/MS, DIA (data-independent acquisition), IMS-enabled workflows |
| Dynamic Range | >5 orders of magnitude |
| Mass Accuracy | <1 ppm with lock-mass calibration |
| Vacuum System | Advanced multi-stage turbomolecular pumping system |
| Interface | Z-Spray, NanoLockSpray ion source |
| Software | UNIFI, MassLynx, Progenesis QI |
| Compliance | 21 CFR Part 11 compatible |