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Waters SELECT SERIES MRT LC-MS with ACQUITY UPLC ultra-high-resolution multi-reflecting time-of-flight mass spectrometer for proteomics, metabolomics, pharmaceutical, biopharmaceutical, and environmental research
  • Key Features:

    • Multi-Reflecting Time-of-Flight (MRT) technology delivering ultra-high resolution and mass accuracy.

    • Resolution exceeding 200,000 FWHM, enabling fine isotopic separation and confident analyte identification.

    • Extended flight path MRT analyzer increases resolution without sacrificing sensitivity or duty cycle.

    • Seamlessly integrated with ACQUITY UPLC for high-efficiency separations.

    • High dynamic range and sensitivity suitable for complex biological, pharmaceutical, and environmental samples.

    • Compatible with ion mobility separation (IMS) workflows for multidimensional molecular characterization.

    • Fully supported by UNIFI scientific information system for compliance, reporting, and streamlined analysis.

  • Applications:

    • Proteomics: High-resolution peptide mapping, PTM characterization, biomarker discovery.

    • Metabolomics & Lipidomics: Untargeted small molecule profiling, structural elucidation.

    • Biopharmaceuticals: Intact mass analysis, glycosylation profiling, impurity/degradation studies.

    • Pharmaceutical Development: Drug metabolism studies, impurity characterization, lead optimization.

    • Environmental & Food Safety: High-resolution screening of trace contaminants and residues.

  • Specifications:

Specification Detail
LC/MS Platform Waters SELECT SERIES MRT LC-MS with ACQUITY UPLC
MS System Type Multi-Reflecting Time-of-Flight (MRT) Hybrid
Mass Range m/z 20–100,000
Resolution >200,000 FWHM
Ionization Modes ESI, NanoESI, APCI, APPI optional
Autosampler ACQUITY UPLC autosampler
Acquisition Modes MS, MS/MS, DIA (data-independent acquisition), IMS-enabled workflows
Dynamic Range >5 orders of magnitude
Mass Accuracy <1 ppm with lock-mass calibration
Vacuum System Advanced multi-stage turbomolecular pumping system
Interface Z-Spray, NanoLockSpray ion source
Software UNIFI, MassLynx, Progenesis QI
Compliance 21 CFR Part 11 compatible

 

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