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Key Features:
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High-resolution TOF analyzer with XS platform, delivering excellent mass accuracy and sensitivity.
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Seamless integration with ACQUITY H-Class UPLC for flexible gradient formation and robust routine separations.
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Resolution of up to 40,000 FWHM with accurate mass measurement (<1 ppm).
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MSE acquisition for simultaneous qualitative and quantitative data collection.
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Wide dynamic range for detecting both low- and high-abundance analytes in a single run.
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QuanTof technology ensures improved duty cycle, sensitivity, and robustness.
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Supported by UNIFI and MassLynx software for compliance-ready workflows.
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Applications:
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Pharmaceuticals: Drug discovery, impurity profiling, metabolite identification.
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Proteomics: Accurate mass protein and peptide identification.
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Metabolomics/Lipidomics: Untargeted and targeted profiling of metabolites and lipids.
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Biopharmaceuticals: Intact protein characterization, glycan profiling, structural analysis.
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Food Safety & Environment: Contaminant screening, residue detection, environmental monitoring.
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Specifications:
| Specification | Detail |
|---|---|
| LC/MS Platform | Xevo G2-XS TOF LC-MS with ACQUITY H-Class UPLC |
| MS System Type | Time-of-Flight (TOF) Mass Spectrometer |
| Mass Range | m/z 20–100,000 |
| Resolution | Up to 40,000 FWHM |
| Ionization Modes | ESI, NanoESI, APCI, APPI optional |
| Autosampler | ACQUITY H-Class UPLC autosampler |
| Acquisition Modes | MS, MS/MS, MSE |
| Dynamic Range | >5 orders of magnitude |
| Mass Accuracy | <1 ppm with lock-mass calibration |
| Vacuum System | Advanced multi-stage turbomolecular pumping system |
| Interface | Z-Spray, NanoLockSpray ion source |
| Software | UNIFI, MassLynx, Progenesis QI |
| Compliance | 21 CFR Part 11 compatible |