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Waters Xevo G2-XS TOF LC-MS with ACQUITY H-Class UPLC high-resolution accurate mass time-of-flight LC/MS system for pharmaceutical, proteomics, metabolomics, food safety, and environmental applications
  • Key Features:

    • High-resolution TOF analyzer with XS platform, delivering excellent mass accuracy and sensitivity.

    • Seamless integration with ACQUITY H-Class UPLC for flexible gradient formation and robust routine separations.

    • Resolution of up to 40,000 FWHM with accurate mass measurement (<1 ppm).

    • MSE acquisition for simultaneous qualitative and quantitative data collection.

    • Wide dynamic range for detecting both low- and high-abundance analytes in a single run.

    • QuanTof technology ensures improved duty cycle, sensitivity, and robustness.

    • Supported by UNIFI and MassLynx software for compliance-ready workflows.

  • Applications:

    • Pharmaceuticals: Drug discovery, impurity profiling, metabolite identification.

    • Proteomics: Accurate mass protein and peptide identification.

    • Metabolomics/Lipidomics: Untargeted and targeted profiling of metabolites and lipids.

    • Biopharmaceuticals: Intact protein characterization, glycan profiling, structural analysis.

    • Food Safety & Environment: Contaminant screening, residue detection, environmental monitoring.

  • Specifications:

Specification Detail
LC/MS Platform Xevo G2-XS TOF LC-MS with ACQUITY H-Class UPLC
MS System Type Time-of-Flight (TOF) Mass Spectrometer
Mass Range m/z 20–100,000
Resolution Up to 40,000 FWHM
Ionization Modes ESI, NanoESI, APCI, APPI optional
Autosampler ACQUITY H-Class UPLC autosampler
Acquisition Modes MS, MS/MS, MSE
Dynamic Range >5 orders of magnitude
Mass Accuracy <1 ppm with lock-mass calibration
Vacuum System Advanced multi-stage turbomolecular pumping system
Interface Z-Spray, NanoLockSpray ion source
Software UNIFI, MassLynx, Progenesis QI
Compliance 21 CFR Part 11 compatible

 

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