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Agilent 1100 Series HPLC System with quaternary pump, autosampler, column oven, VWD, and RID detectors versatile modular HPLC solution for pharmaceutical, food, environmental, chemical, and clinical applications.
  • Key Features:

    • Modular Agilent 1100 HPLC system configured with quaternary pump, autosampler, column oven, variable wavelength detector (VWD), and refractive index detector (RID).

    • Quaternary pump allows mixing of up to four solvents with isocratic or gradient elution, supporting flexible method development.

    • High-pressure mixing with vacuum degassing ensures stable baselines and reproducible chromatography.

    • Autosampler with precise programmable injection volumes and high sample capacity for unattended operation.

    • Column oven (thermostatted compartment) provides precise temperature control for reproducible retention times and improved chromatographic resolution.

    • Variable Wavelength Detector (VWD):

      • Selectable wavelength monitoring in the 190–600 nm range.

      • High sensitivity for analytes with UV absorbance, ideal for pharmaceuticals, organics, and biomolecules.

    • Refractive Index Detector (RID):

      • Universal detector for compounds lacking strong chromophores (e.g., sugars, polymers, alcohols, organic acids).

      • High-stability optical bench for accurate and reproducible measurements.

    • Supports a wide range of chromatographic modes: reversed-phase, normal-phase, ion-exchange, size-exclusion, and specialty columns.

    • Fully integrated with Agilent ChemStation software for system control, data processing, quantitation, reporting, and 21 CFR Part 11 compliance.

    • Reliable, rugged, and widely adopted for both research and regulated environments.

  • Applications:

    • Pharmaceutical & Biotech: Assay and impurity testing, drug stability studies, active pharmaceutical ingredient (API) analysis, formulation testing.

    • Food & Beverage: Sugars, organic acids, alcohols, additives, preservatives, sweeteners, and quality control testing.

    • Environmental Analysis: Pesticides, herbicides, and water-soluble pollutants not strongly UV-absorbing.

    • Chemical & Industrial: QA/QC of raw materials, specialty chemicals, surfactants, and polymers.

    • Clinical & Biomedical Research: Analysis of carbohydrates, nucleotides, and compounds with weak UV absorbance.

    • Academic & R&D Laboratories: Teaching, method development, and general-purpose chromatography research.

  • Specifications:

Parameter Specification
System Type High-Performance Liquid Chromatography (HPLC)
Pump Quaternary gradient pump, 4-solvent mixing
Flow Range Typically 0.001–10 mL/min
Pressure Range Up to 400 bar (quaternary pump)
Degasser Integrated vacuum degassing unit
Autosampler Injection range: 0.1–100 µL programmable, high sample tray capacity
Column Oven Thermostatted, 10–80°C (extendable with options)
Variable Wavelength Detector (VWD) Wavelength range: 190–600 nm, selectable single wavelength monitoring
Refractive Index Detector (RID) Universal detection, high-stability optics, suitable for non-UV analytes
Software Agilent ChemStation, OpenLab CDS
Compliance GLP/GMP, 21 CFR Part 11


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