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Key Features:
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The Agilent 6540 Q-TOF LC/MS provides high-resolution accurate mass (HRAM) performance, ideal for advanced qualitative and quantitative analysis.
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Achieves >40,000 FWHM resolution with dual reference mass correction for sub-ppm mass accuracy.
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Incorporates Agilent Jet Stream (AJS) technology for enhanced ionization efficiency and improved sensitivity.
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Offers fast acquisition speeds (up to 50 spectra/sec) to handle complex LC peaks without loss of data quality.
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Supports full MS, MS/MS, and data-independent acquisition (DIA) workflows for both discovery and targeted studies.
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Capable of handling a wide dynamic range, enabling trace-level detection alongside high-abundance compounds.
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Fully compatible with Agilent LC systems and MassHunter software for data processing, compliance, and reporting.
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Designed for regulated environments with 21 CFR Part 11 compliance.
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Applications:
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Proteomics & Metabolomics: Biomarker discovery, metabolic profiling, pathway analysis.
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Pharmaceutical Research: Drug discovery, impurity analysis, ADME studies.
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Food Safety & Quality: Screening for contaminants, authenticity testing, residue monitoring.
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Environmental Testing: Detection of pollutants, pesticides, and trace contaminants.
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Advanced Chemical Research: Structure elucidation of small molecules, peptides, and natural products.
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Specifications:
| Specification | Detail |
|---|---|
| MS Type | Quadrupole Time-of-Flight (Q-TOF) Mass Spectrometer |
| Resolving Power | >40,000 FWHM |
| Mass Range | m/z 20–20,000 |
| Mass Accuracy | ≤ 2 ppm with dual reference mass correction |
| Ionization Modes | ESI, APCI, Dual Agilent Jet Stream (AJS) |
| Dynamic Range | ≥ 5 orders of magnitude |
| Acquisition Modes | Full scan MS, MS/MS, Data-independent acquisition (DIA) |
| Scan Speed | Up to 50 spectra/sec |
| Vacuum System | High-efficiency turbomolecular pump |
| Interface | Orthogonal spray with optimized ion optics |
| Software | Agilent MassHunter Suite (Qualitative & Quantitative) |
| Compliance | 21 CFR Part 11, GLP, GMP |