Skip to product information
Agilent 6546 LC/Q-TOF with 1260 Infinity II LC high-resolution accurate-mass quadrupole time-of-flight LC/MS system delivering >60,000 FWHM resolution and sub-ppm accuracy, ideal for metabolomics, pharmaceutical development, proteomics, and food safety research.
  • Agilent 6546 LC/Q-TOF with 1260 Infinity II LC high-resolution accurate-mass quadrupole time-of-flight LC/MS system delivering >60,000 FWHM resolution and sub-ppm accuracy, ideal for metabolomics, pharmaceutical development, proteomics, and food safety research.
  • Agilent 6546 LC/Q-TOF with 1260 Infinity II LC high-resolution accurate-mass quadrupole time-of-flight LC/MS system delivering >60,000 FWHM resolution and sub-ppm accuracy, ideal for metabolomics, pharmaceutical development, proteomics, and food safety research.
Agilent 6546 LC/Q-TOF with 1260 Infinity II LC High-Resolution LC-MS for Metabolomics & Pharmaceutical Research
$0.00

  • Key Features:

    • The Agilent 6546 LC/Q-TOF with 1260 Infinity II LC combines ultra-high-resolution Q-TOF mass spectrometry with the reliability of Agilent’s 1260 Infinity II LC system for metabolomics, proteomics, and pharmaceutical research.

    • Provides >60,000 FWHM resolution and sub-1 ppm mass accuracy, ensuring precise identification of metabolites and drug compounds in complex samples.

    • Integrated Agilent Jet Stream Technology and dual ion funnel optics maximize sensitivity and signal stability.

    • Supports fast acquisition speeds (up to 50 spectra/sec) to match rapid UHPLC gradients from the 1260 Infinity II LC.

    • Broad mass range (m/z 20–20,000) allows analysis of both small molecules and large biomolecules.

    • Compatible with Data-Independent Acquisition (DIA), full scan MS, targeted MS/MS, and quantitative workflows.

    • The 1260 Infinity II LC provides robust, precise, and reproducible separations, ensuring seamless integration with the Q-TOF system.

    • Powered by Agilent MassHunter software, supporting compliance-ready data acquisition and analysis (21 CFR Part 11).

  • Applications:

    • Metabolomics: Comprehensive metabolite profiling, biomarker discovery, systems biology.

    • Pharmaceutical Development: Drug metabolism, pharmacokinetics, impurity profiling.

    • Proteomics: Protein identification, PTM characterization, high-resolution biomarker research.

    • Food Safety & Quality: Screening for contaminants, authenticity verification.

    • Environmental Science: Monitoring trace pollutants and emerging contaminants.

  • Specifications:

Specification Detail
MS Type Quadrupole Time-of-Flight (Q-TOF) LC/MS
LC System Agilent 1260 Infinity II LC – UHPLC with precise gradient control
Resolution >60,000 FWHM
Mass Accuracy ≤1 ppm with dual-reference correction
Mass Range m/z 20–20,000
Ionization Sources ESI, APCI, Dual AJS (Agilent Jet Stream)
Dynamic Range ≥ 5 orders of magnitude
Acquisition Modes Full scan, MS/MS, DIA, targeted quantitation
Scan Speed Up to 50 spectra/sec
Software Agilent MassHunter (Qualitative & Quantitative analysis)
Compliance 21 CFR Part 11, GMP, GLP


You may also like