Key Features:

• The Agilent 6546 LC/Q-TOF with 1290 Infinity II UHPLC delivers ultra-high-resolution accurate-mass Q-TOF performance combined with fast, precise, and high-throughput separations from the 1290 Infinity II UHPLC.

• Offers >60,000 FWHM resolution with ≤1 ppm mass accuracy, enabling confident compound characterization even in complex biological matrices.

• Enhanced with Agilent Jet Stream ionization and dual ion funnel technology, ensuring maximum sensitivity and ion transmission efficiency.

• Broad mass range (m/z 20–20,000) accommodates small molecules, peptides, metabolites, and intact proteins.

• Supports acquisition speeds up to 50 spectra/sec, ideal for narrow UHPLC peaks.

• Features Data-Independent Acquisition (DIA), targeted MS/MS, and comprehensive full-scan modes for discovery and quantitation workflows.

• The 1290 Infinity II UHPLC enables ultra-fast gradients, superior chromatographic resolution, and high reproducibility, perfectly complementing the Q-TOF’s analytical power.

• Integrated with Agilent MassHunter software for advanced data processing, compliance support (21 CFR Part 11), and seamless reporting.

Applications:

• Pharmaceutical & Biopharma: Drug metabolism, PK/PD studies, impurity analysis, biologics characterization.

• Metabolomics & Lipidomics: High-resolution metabolite and lipid profiling, biomarker discovery.

• Proteomics: Protein identification, PTM analysis, biomarker validation.

• Food Safety & Quality Control: Contaminant detection, authenticity and adulteration testing.

• Environmental Research: Emerging contaminant detection, trace-level pollutant monitoring.

Specifications: