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Key Features:
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The Agilent 6550 iFunnel Q-TOF LC/MS with 1260 Infinity II LC is a high-sensitivity accurate-mass Q-TOF system designed for advanced proteomics, metabolomics, and pharmaceutical research.
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Integrates iFunnel Technology to maximize ion transmission efficiency, delivering up to 10x sensitivity gains over conventional Q-TOF systems.
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Paired with the Agilent 1260 Infinity II LC, providing reliable UHPLC performance, precise gradients, and robust sample handling.
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Achieves >40,000 FWHM resolution with <2 ppm mass accuracy, ensuring accurate compound identification in complex matrices.
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Equipped with Agilent Jet Stream Technology for enhanced ionization and improved signal-to-noise ratio.
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Fast acquisition speeds (up to 50 spectra/sec) allow high-throughput analyses of narrow UHPLC peaks.
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Supports flexible acquisition modes (full scan, DIA, targeted MS/MS) for discovery and quantitation workflows.
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Controlled with Agilent MassHunter software, offering compliance-ready data management for 21 CFR Part 11 environments.
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Applications:
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Proteomics: Protein identification, PTM analysis, biomarker discovery.
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Metabolomics: Metabolite profiling, biomarker validation, systems biology.
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Pharmaceutical R&D: Drug metabolism, PK/PD studies, impurity profiling.
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Food Safety & Quality Control: Detection of contaminants, authenticity testing.
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Environmental Analysis: Trace-level detection of pollutants and emerging contaminants.
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Specifications:
| Specification | Detail |
|---|---|
| MS Type | Quadrupole Time-of-Flight (Q-TOF) Mass Spectrometer |
| LC System | Agilent 1260 Infinity II LC – high-performance UHPLC |
| Resolution | >40,000 FWHM |
| Mass Range | m/z 20–20,000 |
| Mass Accuracy | ≤ 2 ppm with dual reference correction |
| Ionization Sources | ESI, APCI, Dual AJS (Agilent Jet Stream) with iFunnel ion optics |
| Dynamic Range | ≥ 5 orders of magnitude |
| Acquisition Modes | Full scan, MS/MS, Data Independent Acquisition (DIA) |
| Scan Speed | Up to 50 spectra/sec |
| Software | Agilent MassHunter (Qualitative & Quantitative analysis) |
| Compliance | 21 CFR Part 11, GMP, GLP |