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Agilent 6550 iFunnel Q-TOF LC/MS with 1260 Infinity II LC high-resolution, accurate-mass quadrupole time-of-flight LC-MS system with iFunnel technology and Infinity II UHPLC for proteomics, metabolomics, pharmaceutical, and environmental research.
  • Key Features:

    • The Agilent 6550 iFunnel Q-TOF LC/MS with 1260 Infinity II LC is a high-sensitivity accurate-mass Q-TOF system designed for advanced proteomics, metabolomics, and pharmaceutical research.

    • Integrates iFunnel Technology to maximize ion transmission efficiency, delivering up to 10x sensitivity gains over conventional Q-TOF systems.

    • Paired with the Agilent 1260 Infinity II LC, providing reliable UHPLC performance, precise gradients, and robust sample handling.

    • Achieves >40,000 FWHM resolution with <2 ppm mass accuracy, ensuring accurate compound identification in complex matrices.

    • Equipped with Agilent Jet Stream Technology for enhanced ionization and improved signal-to-noise ratio.

    • Fast acquisition speeds (up to 50 spectra/sec) allow high-throughput analyses of narrow UHPLC peaks.

    • Supports flexible acquisition modes (full scan, DIA, targeted MS/MS) for discovery and quantitation workflows.

    • Controlled with Agilent MassHunter software, offering compliance-ready data management for 21 CFR Part 11 environments.

  • Applications:

    • Proteomics: Protein identification, PTM analysis, biomarker discovery.

    • Metabolomics: Metabolite profiling, biomarker validation, systems biology.

    • Pharmaceutical R&D: Drug metabolism, PK/PD studies, impurity profiling.

    • Food Safety & Quality Control: Detection of contaminants, authenticity testing.

    • Environmental Analysis: Trace-level detection of pollutants and emerging contaminants.

  • Specifications:

Specification Detail
MS Type Quadrupole Time-of-Flight (Q-TOF) Mass Spectrometer
LC System Agilent 1260 Infinity II LC – high-performance UHPLC
Resolution >40,000 FWHM
Mass Range m/z 20–20,000
Mass Accuracy ≤ 2 ppm with dual reference correction
Ionization Sources ESI, APCI, Dual AJS (Agilent Jet Stream) with iFunnel ion optics
Dynamic Range ≥ 5 orders of magnitude
Acquisition Modes Full scan, MS/MS, Data Independent Acquisition (DIA)
Scan Speed Up to 50 spectra/sec
Software Agilent MassHunter (Qualitative & Quantitative analysis)
Compliance 21 CFR Part 11, GMP, GLP



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