Key Features:

• Dual-Source Technology: Integrated MALDI-2 laser post-ionization with ESI (CaptiveSpray nanoESI), enabling both imaging MS and traditional LC-MS/MS in one system.

• MALDI-2 Post-Ionization: Dramatically enhances ion yields for lipids, metabolites, glycans, and peptides in imaging workflows.

• Trapped Ion Mobility Spectrometry (TIMS): Provides 4D molecular separation by retention time, m/z, intensity, and ion mobility.

• QTOF High Resolution: Delivers >60,000 FWHM resolution with <1 ppm mass accuracy for reliable compound identification.

• Versatile Workflows: Switch between spatial omics imaging and UHPLC-MS/MS proteomics on a single platform.

• High Sensitivity: Detects low-abundance species with improved signal-to-noise from MALDI-2 ionization.

• PASEF Support: When operated in LC-MS/MS mode, uses Parallel Accumulation Serial Fragmentation for ultra-fast proteomics.

• Advanced Imaging: Enables molecular histology, lipidomics, drug distribution, and tumor microenvironment mapping.

• Regulatory Ready: 21 CFR Part 11 compliant for pharmaceutical and clinical applications.

Applications:

• Spatial Omics & Imaging Mass Spectrometry: High-resolution mapping of metabolites, lipids, peptides, and proteins in tissue.

• Proteomics & Biomarker Discovery: PASEF-enabled high-throughput LC-MS/MS for deep proteome coverage.

• Clinical & Translational Research: Mapping of disease biomarkers directly in tissue context.

• Pharmaceutical R&D: Drug distribution and metabolism studies in tissue environments.

• Metabolomics & Lipidomics: Enhanced MALDI-2 sensitivity for small molecule and lipid imaging.

• Multi-Omics Integration: Combines imaging MS with proteomics for comprehensive biological insights.

Specifications (Table):