Key Features:

• Integrated High-Performance Platform: Combines Bruker’s timsTOF Pro QTOF mass spectrometer with the Bruker Elute UHPLC for complete LC-MS/MS workflows.

• Trapped Ion Mobility Spectrometry (tims): Adds an orthogonal separation dimension for precise differentiation of isomers and complex peptide mixtures.

• PASEF Technology (Parallel Accumulation Serial Fragmentation): Boosts sequencing speed and sensitivity, enabling high proteome coverage.

• High Resolution & Accuracy: Delivers >60,000 FWHM resolution and <1 ppm internal mass accuracy.

• Elute UHPLC Advantages: Optimized for nano, micro, and analytical scale separations with superior gradient precision and reproducibility.

• 4D Proteomics Capability: Integration of ion mobility, retention time, mass-to-charge, and intensity for ultra-deep proteome analysis.

• Quantitative Flexibility: Supports DIA, DDA, PRM, and label-free quantitation workflows.

• Extended Dynamic Range: Captures both low-abundance biomarkers and high-intensity peptides.

• Proven Robustness: Designed for continuous operation in high-throughput proteomics facilities.

• Comprehensive Software: Compatible with ProteoScape, MaxQuant, PEAKS, and Spectronaut for end-to-end data analysis.

• Regulatory Compliance: Supports 21 CFR Part 11 for GxP and pharmaceutical workflows.

Applications:

• Proteomics Research: In-depth protein identification, biomarker discovery, and quantitative proteomics.

• Clinical & Translational Studies: High-resolution proteome profiling for disease research.

• Pharmaceutical Development: Biotherapeutics characterization, drug metabolism, and PK/PD studies.

• Metabolomics & Lipidomics: High-resolution detection of small molecules and lipids with ion mobility separation.

• Food & Environmental Testing: Detection of trace contaminants with high sensitivity.

• High-Throughput Precision Medicine: Scalable workflows for large-cohort proteomic studies.

Specifications (Table):