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Key Features:
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Trapped Ion Mobility Spectrometry (TIMS) combined with Parallel Accumulation–Serial Fragmentation (PASEF) for ultra-high sensitivity and speed.
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Integrated with Evosep One LC for robust, high-throughput sample loading and separation.
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4D proteomics workflow enables separation by retention time, mass-to-charge ratio, ion mobility, and intensity.
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Exceptional quantitative reproducibility for large cohort proteomic studies.
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High duty cycle with minimal sample carryover, ideal for clinical proteomics.
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Optimized for deep proteome coverage with improved peptide and protein identifications.
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Compact, robust design suitable for core labs, pharma, and research centers.
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Applications:
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Large-scale quantitative proteomics and biomarker discovery.
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Clinical research and translational medicine studies.
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Pharmaceutical drug development and biomarker validation.
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Systems biology and pathway analysis.
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Deep tissue proteomics, cancer research, and personalized medicine.
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High-throughput proteomic workflows with low sample consumption.
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Specifications:
Parameter | Specification |
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LC Platform | Evosep One LC with predefined high-throughput gradient methods |
MS System Type | Quadrupole Time-of-Flight (QTOF) with Trapped Ion Mobility Spectrometry (TIMS) |
Ionization Modes | ESI (Electrospray Ionization), positive/negative mode |
Autosampler | Integrated with Evosep One LC (nanoflow, high-throughput sample loader) |
Acquisition Modes | PASEF, DDA (Data-Dependent Acquisition), DIA (Data-Independent Acquisition) |
Dynamic Range | >5 orders of magnitude |
Mass Accuracy | <1 ppm (internal calibration) |
Resolving Power | >60,000 FWHM |
Vacuum System | Multi-stage turbo pumps optimized for QTOF and TIMS stability |
Interface | CaptiveSpray nanoBooster source (nanospray ionization) |
Software | Bruker Compass, DataAnalysis, MaxQuant, Spectronaut compatibility |
Compliance | 21 CFR Part 11 ready |