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Bruker timsTOF SCP with nanoElute UHPLC ultra-sensitive TIMS-QTOF LC-MS/MS system for single-cell proteomics, trace proteomics, and biomarker discovery with PASEF and 4D proteomics technology.
  • Bruker timsTOF SCP with nanoElute UHPLC ultra-sensitive TIMS-QTOF LC-MS/MS system for single-cell proteomics, trace proteomics, and biomarker discovery with PASEF and 4D proteomics technology.
  • Bruker timsTOF SCP with nanoElute UHPLC ultra-sensitive TIMS-QTOF LC-MS/MS system for single-cell proteomics, trace proteomics, and biomarker discovery with PASEF and 4D proteomics technology.
Bruker timsTOF SCP with nanoElute UHPLC High-Sensitivity Single-Cell Proteomics LC-MS/MS System
$0.00

Key Features:

  • Integrated UHPLC-MS Platform: Combines the Bruker timsTOF SCP with the nanoElute UHPLC, optimized for ultra-low input proteomic workflows.

  • Single-Cell Proteomics Capability: Designed for trace proteomics from individual cells or sub-ng protein levels.

  • nanoElute UHPLC Performance: Delivers stable nanoflow gradients, low dead volume, and ultra-high sensitivity for maximum peptide recovery.

  • 4D Proteomics with TIMS: Adds ion mobility separation for superior selectivity and depth of coverage.

  • PASEF Acquisition: >100 Hz MS/MS rate with minimal sample consumption.

  • High Mass Resolution & Accuracy: >60,000 FWHM and <1 ppm accuracy.

  • Compact & Efficient: Streamlined benchtop system with minimal footprint for advanced single-cell proteomics labs.

  • Optimized for Throughput: Stable retention times and reproducibility for large-scale studies.

Applications:

  • Single-Cell Proteomics: Profiling protein expression at the individual cell level.

  • Trace Proteomics: Analysis of ultra-low input samples from scarce or rare biological sources.

  • Biomarker Discovery: Early disease detection from precious clinical samples.

  • Precision Medicine: Stratification of patients using proteomic heterogeneity data.

  • Cancer & Immunology Research: Characterizing tumor heterogeneity and immune cell responses.

  • Stem Cell & Neuroscience Studies: Proteomic profiling of rare or developmental cell populations.

  • Drug Development: Pharmacokinetics/pharmacodynamics with limited sample availability.

Specifications (Table):

Parameter Specification
MS Type TIMS-QTOF (Trapped Ion Mobility Quadrupole TOF)
UHPLC System Bruker nanoElute UHPLC
Sensitivity Ultra-sensitive, optimized for single-cell workflows
Resolution >60,000 FWHM
Mass Accuracy <1 ppm with internal calibration
Mass Range m/z 20 – 20,000
Acquisition Speed >100 Hz with PASEF
Ion Mobility TIMS 4D proteomics separation
LC Flow Rate Nano-flow (50–500 nL/min)
Autosampler Integrated with nanoElute UHPLC, low-volume injection
Software Bruker ProteoScape, MaxQuant, Compass HyStar, PEAKS
Compliance Supports 21 CFR Part 11
Key Advantage End-to-end single-cell proteomics system with maximum sensitivity

 

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