Key Features:

• Next-Generation TIMS-QTOF: Successor to the timsTOF Pro series, offering enhanced sensitivity and resolution for deep proteomic coverage.

• High-Sensitivity Design: Optimized ion optics and source configuration for low-input proteomics including single-cell and trace-level studies.

• 4D Proteomics: Incorporates ion mobility separation (TIMS) to deliver retention time, m/z, ion mobility, and intensity dimensions.

• PASEF Technology: Parallel Accumulation–Serial Fragmentation enables >120 Hz MS/MS acquisition speed with minimal ion loss.

• Ultra-High Dynamic Range: Detects both high- and low-abundance proteins in complex samples.

• Improved Instrument Stability: Advanced electronics and vacuum system ensure reproducibility across large-scale studies.

• Compact Bench-Top Design: High-resolution, ultra-sensitive system with a small footprint for proteomics and clinical labs.

• Software Ecosystem: Seamless integration with Bruker ProteoScape, PEAKS, MaxQuant, and other advanced proteomics data analysis pipelines.

• Future-Proof Platform: Built to support next-generation proteomics workflows such as single-cell, spatial omics, and biomarker discovery.

Applications:

• Deep Proteome Profiling: High-sensitivity proteomics for comprehensive protein identification.

• Single-Cell Proteomics: Enables quantitative analysis from extremely limited biological material.

• Biomarker Discovery & Validation: Supports clinical and translational research workflows.

• Precision Medicine Research: Stratifying patients by proteomic signatures for diagnostics and therapy development.

• Pharmaceutical & Biotech R&D: Drug target validation, PK/PD studies, and mechanism-of-action research.

• Systems Biology & Functional Proteomics: Exploring protein networks, signaling pathways, and cellular heterogeneity.

• High-Throughput Clinical Proteomics: Reliable and reproducible measurements for large sample cohorts.

Specifications (Table):