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The Cytiva ÄKTA Flux S is a compact, semi-automated tangential flow filtration (TFF) system optimized for lab-scale concentration and diafiltration of proteins, antibodies, and nucleic acids. Engineered for ease of use and flexible setup, it supports filtration and buffer exchange workflows with precision and low dead volume.
Key Features
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Semi-Automated TFF Design: Manual three-way valves for sample, permeate, and waste handling – ideal for small-batch UF/DF applications.
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Wide Flow Range Compatibility: Supports flow rates up to approximately 100 mL/min (application dependent).
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Efficient Filter Management: Manual pressure control valves ensure smooth operation and precise pressure regulation.
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Stirred Reservoir System: 0.5 L reservoir with built-in magnetic stirrer ensures uniform mixing and accurate volume measurements.
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Multiple Filter Options: Compatible with both hollow fiber cartridges and filter cassettes for microfiltration and ultrafiltration.
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Process Data Logging: Integrated USB interface for exporting run data and system diagnostics.
Applications
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Protein and antibody concentration (UF)
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Buffer exchange and diafiltration (DF)
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Filter screening and condition optimization at lab scale
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Clarification and recovery of biological samples
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Development of scalable TFF protocols
Specifications
| Feature | Details |
|---|---|
| System Type | Semi-automated tangential flow filtration (TFF) system |
| Reservoir Volume | 0.5 L with magnetic stirrer and weight-based monitoring |
| Flow Rate Capability | Up to ~100 mL/min (depending on filter/application) |
| Pressure Control | Manual retentate and permeate pressure valves |
| Valve Type | Manual three-way valves (sample/recovery/waste) |
| Filter Compatibility | Hollow fiber cartridges and filter cassettes (microfiltration/ultrafiltration) |
| Data Export | USB port for process logs and system diagnostics |
| Control Interface | Built-in touch panel for operation and monitoring |
Summary
The Cytiva ÄKTA Flux S is a reliable, lab-scale UF/DF solution, offering flexibility, precise control, and scalability. Its compact design, efficient filter compatibility, and user-friendly interface make it ideal for protein purification, buffer exchange, and small-scale process development.