Pickup currently not available
Key Features:
-
QTRAP Hybrid Design: Combines triple quadrupole quantitation with linear ion trap scanning for enhanced versatility.
-
Exceptional Sensitivity: fg-level detection with Stable Ion Drive™ technology for consistent signal response.
-
Turbo V™ Source: Rugged, high-efficiency ionization source supporting both ESI and APCI.
-
Fast Polarity Switching: <5 ms for seamless analysis of compounds requiring both positive and negative modes.
-
High-Speed MRM Performance: Handles large panels with up to 20,000+ MRM transitions/sec.
-
Dynamic Range: Wide linear range covering low- to high-abundance analytes (>5–6 orders of magnitude).
-
Advanced Scan Functions: MRM³, Enhanced MS (EMS), Enhanced Product Ion (EPI), Product Ion scans for qualitative/quantitative workflows.
-
SelexION® (optional): Differential mobility separation for additional selectivity in complex samples.
-
Robust Collision Cell: Linear accelerator collision cell with fast ion transmission and efficient fragmentation.
-
Software Ecosystem: SCIEX OS for acquisition, quantitation, data review, automation, and compliance.
-
Compliance: FDA 21 CFR Part 11 support, GLP/GMP ready.
Applications:
-
Pharmaceutical & Biopharma: Quantitative bioanalysis (PK/PD), drug metabolism (DMPK), impurity profiling, biomarker quantitation.
-
Clinical & Forensic Toxicology: Drug monitoring, toxicological screening, metabolite identification.
-
Food Safety Testing: Pesticide residues, veterinary drugs, mycotoxins, food contaminants.
-
Environmental Analysis: Pollutant monitoring, water quality testing, emerging contaminants.
-
Proteomics & Metabolomics: Targeted quantitation of metabolites, peptides, and biomarkers.
Specifications (Table):
| Parameter | Specification |
|---|---|
| System Configuration | SCIEX QTRAP 6500 LC-MS/MS |
| MS Type | Hybrid Triple Quadrupole / Linear Ion Trap |
| Mass Range | m/z ~5 – 2000 |
| Resolution | Unit resolution (0.7 Da FWHM) |
| Dynamic Range | >5–6 orders of magnitude |
| Ionization Modes | ESI, APCI (Turbo V™ Source) |
| Polarity Switching | <5 ms |
| Acquisition Modes | MRM, Scheduled MRM™, MRM³, EMS, EPI, Product Ion Scans |
| MRM Transition Speed | 20,000+ transitions/sec |
| Sensitivity | fg-level detection (compound dependent) |
| Collision Cell | Linear accelerator collision cell with QJet® ion guide |
| Vacuum System | Turbo molecular pump system |
| Interface | Turbo V™ Source with optional SelexION® |
| Software | SCIEX OS |
| Compliance | 21 CFR Part 11, GLP/GMP support |